Study On The Relationship Between The High Incidence Of Lung Cancer And The Local Coal - Burning Environment And Coal Combustion Products In

Atmosphere is an indispensable natural resource for human.However, with the rapid development of human beings, they has neglected the protection of the atmosphere, and even caused serious air pollution.Many human respiratory diseases are closely related to air pollution, among which the most serious malignant disease is lung cancer. At the end of the 20 th century, the lung cance mortality is the highest among all kinds of cancer. Xuanwei is one of the highest areas of lung cancer mortality in our country, especially in female lung cancer mortality, which belongs to the forefront in the world.Numerous studies show that the high incidence of lung cancer is closely related with the use of Xuanwei local bituminous coal. In this paper, uses the theory and method of medical geology, environmental geoscience, cell toxicology, geochemistry, and geology, to analyze the local bituminous coal accumulating environment, on this basis, uses the ICP-MS and other equipment to test element content of lung cancer tissue in lung cancer patients, local bituminous coal, and bituminous products, compares element content of bituminous products with lung cancer tissue in lung cancer patients. Through the above analysis and research, the main results are obtained:1 The coal of residents in Xuanwei Hutou village using is from a nearby coal mine, this area belongs to the Late Permian coal district. And the coal accumulation environment is mainly influenced by the two factors, the ancient structure and sedimentary environment.(1) In the ancient structure, the Dongwu movement and large-scale basaltic eruption constructed sedimentary basement tectonics of Late Permian. In the formation of coal, volcanic activity also played a certain role in the control. Large scale volcanic eruption, often formed a thicker tuffaceous bed and thin coal seam; smaller volcanic eruptions, could not form a volcanic rock, but eruption of volcanic material deposited in the coal seam, formed Tonstein. Studies show that the volcanic ash deposition into peat bog often leads to the enrichment of elements in coal.(2) In the sedimentary environment, the piedmont alluvial plain location, the tall trees in Late Permian, hot and humid rainforest climate provided favorable conditions for the formation of coal.2 Tests element content of bituminous coal in Xuanwei Hutou village, and compares with domestic and foreign coal elements.(1) Compares with US coal trace elements,V, Cr, Mn, Co, Ni, Cu, Ga, Pb and other trace elements content were higher than the United States, especially V and Mn, which is the 5.75 times and 15.47 times than the United States. As, Ba, Zn and other elements content is less than the United States, Cr, Cd, Sb and other elements is quite of the US.(2) Compared with the arithmetic mean of trace elements content in our country, trace elements V, Cr, Mn, Co, Ni, Cu and other content of local bituminous coal are higher than the national average,the average content of V is 2.37 times than the national average, Mn is 5.16 times, Co is 2.21 times, Ni is 3.16 times, Cu is 2.54 times. The enrichment of these elements is mostly related to the volcanic activity, the ash deposition into the coal seam, leading to the enrichment of these elements.3 Collects indoor particulate matter of Xuanwei Hutou village by LPI13 level classification sampler, finds that the particle size of indoor particulate matter is lesser than1.1μm, and accounts for 68.44%. Indoor particulate matter concentration: Morning> Afternoon> Night.4 Collects bituminous products of local coal in Hutou village, include chimney dust, indoor dust, bottom ash and stove ash, tests element content of various dust samples by ICP-MS, and compared with the element content of local coal.(1) The elements content of K, Mg, Na, P, Zn, Ba, Ni, Ga, Ge, Sr, Pt, Tl, U and so on, enrich in chimney dust. The elements content of Fe, Mn, Ca, Al, V, Li, Be, Co, Cu, Y, Nd, Sm, Eu, Gd, et al, enrich in stove ash. The elements content of Fe, Mg, Ca, Ti, Cr, Sr, La, and so on enrich in indoor dust. The elements content of S, higher Pb, Ag, Rb, Cd, Sn, Sb, Cs, Bi, et al, enrich in bottom ash.(2) Compares the elements content of various dust samples, element enrichment order is chimney dust, stove ash, indoor dust and bottom ash.(3) Compares the elements content of various dust samples with local coal, the result show that most elements distribution trend is consistent, but the content of elements is somewhat different. The elements content of dust is substantially higher than local coal. So, coal combustion will lead to enrichment of elements content in combustion products.5 Observes lung cancer tissues, adjacent tissues and normal tissue of lung cancer patients by TEM-EDX. Finds that the particles are widely distributed in lung tissues, and most are nanoscale particle size, which agglomerate together with various form. Test the element content in lung tissues of Xuanwei lung cancer patients, and the finding shows that the order of average content of elements in lung tissues is cancer tissue, adjacent tissues, normal tissues. And the content of elements in cancer tissue is very high. Among all the elements in cancer tissue, the content of Cr and Ni is 2.17 times and 2.14 times than normal tissue. So, it can be speculated that the high incidence of lung cancer is related to the high content of toxic elements in lung tissue.6 Analyzes the source of element content in lung cancer tissue of lung cancer patients. The element content distributes consistently in lung cancer tissue and dust samples. Therefore, the element content in lung cancer tissues of patients in Xuanwei accumulates mainly from indoor coal burning particulate matter. Thus, the high incidence of lung cancer in Xuanwei directly related to indoor coal-fired product.The residents in Xuanwei Hutou village should use sparingly or not use local bituminous coal.