Research And Application 0f Cep Halosporin Antibiotics In Wastewater Treatment

China is already the world’s largest antibiotic-producing country. In the other way the production of antibiotics is recognized as “high-polluting” industries. To reduce the impact to the environment caused by p Harmaceutical companies, the state a new "fermentative pharmaceutical industrial water pollutant discharge standards"(GB21903-2008) was announced in the year 2008. How to meet the new standards in emission targets for all p Harmaceutical companies is currently facing problem..In this paper,the wastewater of cep Halosporin from a large domestic p Harmaceutical company was studied. Based on the analysis of the generated sources and component of pollution and contamination of the wastewater, two kinds of new generation reactor: immobilized cell bioreactors(ICB) and membrane bioreactor(MBR) were selected to respectively treat the cep Halosporin antibiotic wastewater. According to the major pollutants treatment effect, the optimal operating parameters of both processes were determined. The effluents from bioreactor were treated by deep oxidation process using Fenton oxidation technology and ozone catalytic oxidation technology, and the reaction parameters of orthogonal experimental model were established. Based on the above experiments, economic and technical analysis and comparison was carried out.By contrast pilot test and engineering operating parameters, the preliminary conclusions as follows:1)ICB or MBR + ozone catalytic oxidation or Fenton oxidation can achieve tables 2 emission standard of "Discharge standards of water pollutants for p Harmaceutical industry Fermentation category "(GB21903-2008).2)Based on the comprehensive study of the pollutants generation process of 7-ACA, the advice about wastewater decontamination and clean up triage was given.3) The optimal water HRT of ICB and MBR obtained by experiments respectively was 1.75 d and 2.0d, and ICB and MBR denitrification rate was calculated.4)Through membrane fouling factors experiment to,parameters of using membranes to treat cep Halosporin antibiotic wastewater,such as economic flux,pumping and suction mode and amount of aeration was studied.5) On the base of orthogonal experiment for ozone catalytic oxidation and Fenton oxidation, the optimum operating parameters was determined. Then, the treatment costs per ton and project investment were calculated.This research can provide very meaningful technical support for the same type of cep Halosporin antibiotics wastewater treatment, especially provide a sample for p Harmaceutical companies to archive the new discharge standard.