The Preparation And Biological Application Of Polyhedral Oligomeric Silsesquioxanes-based Conjugated Oligoelectrolyte Nanoparticles

Polyhedral oligomeric silsesquioxanes(POSS) is cage-like nanostructured material that consists of a nanometer-sized siloxane cube. The introduction of POSS into the organic network could remarkably enhance the mechanical and optical properties due to their organic-inorganic hybrid structure. So the POSS harnessed with oligo(p-phenylene vinylene) electrolyte(OPVE) has been synthesized and characterized by NMR, TEM, DLS, FT-IR, UV-PL, PLQY etc al. We got the final product POSS-OPVE nanoparticle with an inert core is well water-soluble, biocompatible, photostable, thermstable, low-toxic et al, which is attributed to the inner POSS core can make the scattered OPVE into integration result in an enhanced performance. Moreover, the three-dimensional POSS core can combine eight-direction OPVE antenna to afford a 3D spherical molecular configuration.This dissertation mainly contains two parts application of POSS-OPVE:1, These POSS-OPVE nanoparticles as Micro Fuel Cell media is sucefully incorporate into E.coli bacterial cell membrane and generates significantly higher power densities. Of practical significance is that the POSS-OPVE NPs is superior to the popular COE, in increasing current generation. This material holds great potential to boost the performance of MFC, suggesting that POSS-COE hybrid material may be discovered that more greatly improve interactions with the charge-collecting electrode.2, we have prepared a novel POSS-derived sensor for sensitive detection of Lipopolysaccharides(LPS) by employing the electrostatic and hydrophobic interactions between the positively charged fluorophore ionic POSS oligo(p-phenylene vinylene) electrolyte(POSS-OPVE) and negatively charged phosphate group in LPS, and the limit of detection of LPS can low as 23 nM.