Preparation, Properties And Application Of Heterocyclic Fluorescence Probe And Optical Functical Complexes

Metal ions play an important role in the surrounding environment and physiological activities of the human body. However, too high or too low concentration of some ions may damage the environment and threaten the health of living beings. Compared with other measurement methods, fluorescence probes are high selectivity, outstanding sensitivity, rapid response. Therefore, it makes sense to design high sensitivity and dissolution probes to detect ions in biological environments. In recent years, optical functional materials have been widely concerned in the areas of human productions and livings as well as high-tech areas for its enormous potential practical application. Optical functional coordination compounds have become an important branch in the field of optical functional materials research owing to its excellent combination properties. In the paper, herein, we successfully prepared new coordination compounds which is self-assembled by the small heterocyclic compounds with Zn(II), Cd(II) salts. Furthermore, the optical properties of the ligand and new coordination compounds were systematically investigated.The concrete research contents are listed as follows:1. Herein, we designed a novel fluorescent turn-on probe for Zn2+, which has a dipicolylamine subunit (abbreviated as DPA) to coordinate with Zn2+ and a triphenylamine benzimidazole group as fluorophore. The experimental results demonstrated that the probe L showed selective and sensitive fluorescence turn-on signaling behavior toward Zn2+ in HEPES buffered (pH=7.4) aqueous solution. The detection limit of this probe was calculated to be 5.10×10-8 M for Zn2+. Fluorescent imaging inside HepG2 cells indicated potential application of the probe for detecting Zn2+ in living cell imaging.2. Here, we have synthesized organic functional ligands Y1, Y2, where 1,3-diazole and 1,2,4-triazole were acted as coordination and electron-donating groups, respectively. Their linear, nonlinear optical property and application in cell imaging were also carefully explored. Both Yl and Y2 with azoles group have multiple coordination sites, by self-assembly of them with zinc(Ⅱ) salts, we afford a series of coordination complexes of Y1. Compared with the free ligands, the complexes show superior luminescent properties, higher fluorescence quantum yield and longer lifetimes in solid state. In addition, complexes have shown nice two-photon absorption activity.3. We synthesized ligand S1 and S2 based on our previous study, where benzoxazole derivatives with excellent optical performance were used as building blocks. Self-assembly of them with Cd(Ⅱ) salts yielded a series of new coordination complexes of S2. Ligand S1, S2 can rotate freely around the single bonds to meet the different geometric requirements of the metal ions and the formation of weak interactions. In addition, the third-order NLO properties of the complexes were investigated in detail, which showed that complexes 1 and 3 may be good candidates for non-linear optical materials.