Study Of Risk Factors And Clinical Symptoms For Sporadic Vibrio Parahaemolyticus Infection In The Shenzhen

ObjectiveTo explore the transmission routes and risk factors of Vibrio Parahaemolyticus in Shenzhen, we conducted an epidemiological survey. This will help to establish the methods monitoring Vibrio Parahaemolyticus infectious diarrhea, and to provide effective practice of prevention and control for it.MethodsA case-control study was conducted based on hospital, from May to September in2011, in the Xixiang People’s hospital of Baoan District, and Longgang District People’s Hospital in Shenzhen. We collected VP cases, diarrhea-cases control and healthy control, which were matched in age and gender without strict1:1matching. A coincident questionnaire was used to collect the information including general information, clinical data, and epidemiological information.Data analysisAll information from questionnaire was input in computer using Epidata3.0software and constructed a database. Then SPSS16.0software was used for data analysis. Statistical significance was designated at P≤0.05.Non-conditional Logistic Model regression was performed to determine contributor on VP in the single factor analysis. After that, we conducted forward method to analysis data in multi-factors analysis.ResultsA total of366specimens (210for male;156for female) were collected from May to September in2011in two specified hospitals. Among them, there were101(27.6%) VP cases,181(49.5%) diarrhea-controls and84(23.0%) healthy-controls. Eating seafood within3days before sick with OR of4.48,(1.09～18.38); eating out for6.26(1.50～26.21); feeling of insanitary for13.78(1.94～97.79) were risk factors of VP infection. On the other hand, Resident population for0.15(0.02～0.93); leftovers for0.02(0.01～0.21); meat for0.05(0.01,0.52); poultry for0.23(0.07,0.79); pickled vegetables for0.12(0.03,0.50); egg and egg products for0.10(0.03,0.35)were protective factors.ConclusionIt has been proved that seafood and unsanitary food are the main risk factors of VP infection. To prevent and control the disasters caused by VP, we must increase awareness and knowledge of Vibrio Parahaemolyticus. Meanwhile, promoting healthy education to residents and eating safe food in sanitary place are also the important measures. In the end, supervision for Food and Beverage services is an urgent duty on Health authorities.