Synthesis And Characterization Of Integrated Pushpin-like Biomimetic Scaffolds

Objective：To prepare the chitosan/polylactic acid/hydroxyapatite integratedscaffolds using solvent-castiing/solt-leaching method， pushpin-like,explore theirapplication in articular cartilage tissue engineering.Methods： Using X-ray diffraction, infrared spectrum,scanning electronmicroscopy, compressive strength and blending strength were adopted to characterizeand analyze the scaffolds.Results：The scaffolds,pushpin-like,are white solid,which have different part ofcartilage and subchondral bone.They have a good porosity and mesh adjustable inSEM。Mechanics performance testing show that their compressive and blendingstrength are in inverse relation to the porosity,but be in direct proportion to theproportion of HA.Conclusion：It is indicated that thescaffolds have a good over-all property andcan be used as a type of bio-engineered stent.