[Objective] Data mining technology as a means to computers, to masters of traditional Chinese medical science and clinical practice of Professor Zhou Zhongying’s life is based on academic achievement, on clinical experience of Professor Zhou Zhongying’s experience on treating Hypertensive disease and inheritance studies academic thinking, differentiation and treatment focuses on the discovery rule and unique experience, to further improve the renal cell carcinoma:clinical efficacy of traditional Chinese medicine to better benefit the majority of patients.[Methods] Outpatient collection of Professor Zhou Zhongying’s nearly7years, from2003to2010, to all electronic medical records in Hypertensive disease, and comprehensive arrangement, and in strict accordance with the inclusion criteria, exclusion criteria for filtering, which comply with the conditions of medical records of300cases (total687diagnosis).300cases of medical record information establishing Zhou Zhongying’s medical records of renal cell carcinoma using SQL-Server2005software database, using frequency distribution, association rules, authentic proof testing and other methods, focusing on mining symptoms, pathogenesis, prescription, prescription, or relevance of the relation between, and comprehensive analysis of the mining results, draw conclusions, the summary. With a view to its diagnosis and treatment of Hypertensive disease: clinical experience of refined academic thought.[results]300patients in138cases of male and162female cases, aged87years old, the largest least29years old, with a mean age of49.3years. Medical record information mining results show that:the main symptoms of hypertension patients with dizziness, headache, head swells, dizziness, tinnitus, flustered, numbness of limbs, face red, be agitated, insomnia and see more; Tongue vein with moss yellow greasy, yellow (tired), mass dark (red) purple, pulse fine (slide) see more. Frequency is highest is dizziness, in687the diagnosis time there were307times,44.7%. Coating on the tongue of the highest frequency is yellow greasy, in687clinical time appeared in477times,69.4%. Pulse slide appeared472times, 68.7%. Pathogenesis involves wind Yang hyperactivity phlegm in the fire, fill, blood disorders, liver and kidney deficiency, blood stasis resistance orifices, Yin and Yang. The highest frequency of occurrence kidney deficiency, for241times,35.08%. Pathological factors involved in wind, phlegm, fire, wet, depression, blood stasis, and virtual, including wind frequency for307times,44.69%; Stasis frequency for266times,37.99%. Using empirical analysis and pathogenesis of logistic regression and five obtains the pathogenesis of combination of five:air Yang hyperactivity:uncaria, gastrodia elata, cassia seed, apocynum venetum leaves, mother of pearl, was, plantain, wild chrysanthemum flower; Phlegm in the fire shing: Chen DanXing, Fried scutellaria baicalensis georgi, selfheal, main stiff silkworm, seaweed, oysters, rhizoma alismatis, Blood disorders:salvia miltiorrhiza, ligusticum wallichii, large (small) thistle, radix achyranthis bidentatae, fairy cane, wide earthworm, red ochre; Liver and kidney Yin deficiency:big virgin soil, wolfberry fruit, main glossy privet, system radix polygoni multiflori, mistletoe, chrysanthemum, white thistle, Blood stasis resistance orifices:ligusticum wallichii, herbaceous peony (paeonia lactiflora), peach kernel, angelica dahurica, calamus, angelica, earthworm, scorpion, Yin not han Yang:a fairy spleen, light congrongtongbian, angelica, eucommia bark and spiritual magnet, phellodendron, cultivated land, Chinese wolfberry.[conclusion] the research results show that high blood pressure pathological factors have seven:wind, phlegm, fire, wet, depression, blood stasis, and virtual, of which the wind is the key. The main mechanism for the imbalance of Yin and Yang, A disease in liver, kidney, heart, and the all have correlation. High blood pressure is divided into six syndrome:(1) the wind Yang hyperactivity phlegm (2) in the fire shing (3) liver and kidney blood disorders (4) Liver-kidney Yin deficiency(5) blood disorder liver-kidney Yin deficiency and blood stasis resistance orifices (6)Deficiency of Yin and Yang. The main therapy have put wind latent Yang, lowering phlegm, regulate qi and activate blood circulation, zi soft liver kidney, promoting blood circulation to remove blood stasis, kidney:temperature raise. Use characteristic:the essencial etiopathogenesis, medicine for trial; Syndrome differentiation and combination of disease should be combined; Pay attention to the dynamic changes of the illness and individual differences, Harmonic qi and Yin and Yang, WenQing and use. |