| ObjectiveBased on57cases of progressive muscular dystrophy patients age, gender, nationality, disease type, disease classification, course of disease, family history and clinical examination were analyzed, the study focuses on30cases of five viscera syndromes distribution pattern and provides the reference for the clinical syndrome differentiation.MethodsAccording to diagnosis standard of progressive muscular dystrophy, collecting a total of progressive muscular dystrophy patients57cases in spleen and stomach department of the First Affiliated Hospital of Guangzhou University of Chinese Medicine out-patient department. According to the diagnostic standard of disease were divided, and the severity of the patients of the performance of grading on the ability of daily life, and the establishment of Excel database. The database was finished by stata12.0and SPSS17.0statistical software, delete and combined treatment of redundant variables and similarity variables, and finally30complete cases data. According to the descriptive statistical analysis and factor analysis on the five viscera syndromes of the30cases complete data.ResultsIn this study, there were50males (87.72%) and7females (12.28%). There were28patients under14years (49.12%),17patients15to30years (29.83%), and12patients>30years (21.05%). There were30patients from Guangdong (52.63%),5patients from Hunan,4patients from Guangxi,3patients from Henan,3patients from Sichuan,2patients from Shanxi, and1patients from Anhui, Beijing, Guizhou, Hainan, Inner Mongolia Hubei, Jiangsu, Jiangxi, Yunnan, Zhejiang.Clinical types are as follows:there are32cases of DMD (56.14%),21cases of BMD (36.84%),2cases of LGMD (3.51%),1case of CMD, and1case of FSHD. According to the patient’s activities of daily living (Barthel index) to evaluate the severity of disease,50patients with grade I (87.72%),3patients with grade II (5.26%),2cases of patients with grade III, and2patients with grade IV.Through the analysis of the patient history information can get the following results:there were9(15.79%) patients had a family history of the disease and48patients without a family history. There were33(57.89%) patients≤5years,19(33.34%) patients with duration of6～15years, and5(8.77%) patients with duration of16-30years. In addition,39patients had EMG,24patients had muscle biopsy,54patients had muscle enzyme examination,13patients had genetic testing.Included in the analysis of five Zang syndromes in patients with a total of30cases, excluding fails to visit patients. The main clinical manifestations of liver syndrome is muscle lesions, such as false hypertrophy, limb pain and numbness and pain in the joints. This collection of patients are mostly in the primary stage of disease is, the less heart syndrome, performance is not obvious, mainly for Shenpifali, occasionally heart palpitations and insomnia. Spleen syndrome mainly temper deficiency, such as limb weakness, fatigue and muscle atrophy. Pulmonary symptoms early in the disease is also the performance is not obvious, the occasional shortness of breath, also relatively more colds in children. The main clinical renal syndrome manifests as a function of the main water deficiency of kidney yang, such as abnormal, Yaoxisuanruan, lumbago, aversion to cold and lordosis.By the factor analysis of syndrome elements of the disease mainly related to phlegm, stasis, heat, wind and false, and to "empty". The main disease in the "spleen","kidney" and "liver". Analysis of the four syndrome types:pi shen liang xu jian tan shi yu zu zheng, pi shen xu ruo zheng, fei qi yin liang xu zheng, gan shen xu sun zheng.GonclusionThe results of this study showed that:the disease more men than women. The age<15years old patients were DMD, and they can take care of themselves. The patients mainly from Guangdong. The compliance compliance of DMD is better than BMD, because BMD patients are mostly adults, and they were lower than the DMD parents enthusiasm. The patients were mainly DMD, so the duration is less than5years accounted for a larger proportion of. All of the patients selected at least two examination method to diagnosis.The five internal organs disease caused the disease, and the five internal organs lesioned between their mutual transmission. The main symptoms of the disease were liver, spleen and kidney symptoms. Main symptoms were pseudohypertrophy, limb weakness, muscle atrophy, joint pain, numbness of limbs, waist pain, lordosis, aversion to cold, relates to the ribs, bone, muscle etc. The heart symptom and lung symptom at the onset stage of the disease were not clear yet, only some sporadic symptoms, such as shen pi Ian yan, easy to catch a cold, shortness of breath, etc. Clinical viscera syndrome conclusion could provide reference for TCM diagnosis and treatment of this disease. The main syndrome of this disease syndromes was deficiency. The main disease of the disease were in the liver and spleen and kidney. The main syndromes of this disease were pi shen liang xu jian tan shi yu zu zheng, pi shen xu ruo zheng, fei qi yin liang xu zheng, gan shen xu sun zheng. |
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