| Objective: through the use of have Bu shen tong luoxifeng Function ofPei-Yuan Tong Nao Capsule to validate the efficacy of clinical safety and efficacy ofthe treatment of PD disease; And then by the effect banking up with Pei-yuanthrough the brain capsule base line to uric acid, expound a doctor of traditionalChinese medicine with UA nourishing kidney exchanging the effect mechanismholding interest wind law in place, for provide effective taking precautions againstand cure the PD method clinically.Methods:This test collection of50patients with Parkinson’s disease deficiencyof kidney and blood stasis,Adopt a random, of equal rank collation follows theresearch being in progress.50regular patients apply simple random law to willdivide into2set,30Patients for treatment group,20Patients as control group.treatment group: Pei-yuan through the brain capsule(Manufacturer:LingRuipharmaceutical co, LTD.Approval number: approved byZ20000022,Specification:0.6g*27grains,3grains at once,3times a day,Period of treatment:4weeks)and addPD Western medicine basic drugs,control group: PD Western medicine basicdrugs.Note:PDWestern medicine basic drugs,Effective doses according toprevious,Adjusted according to clinical effect at any time,4weeks treatmentperiod,Observed before treatment and after4weeks treatment UPDRSⅢScale,UAIndicator assessment,H-Y Classification, scores of TCM syndrome,And treatmentblood tests urine tests,Stool examination,Liver and kidney function and so onDetection of relevant security indicators Before and after experiment.Results:Using the statistical methods to nalysis before and after treatmentefficacy, safety and adverse reactions,The results suggest:Through the use of have bushen tong luoxifeng Function of Pei-yuan through the brain capsul and add PD Western medicine basic drugs treatment can significantly improve symptoms ofkidney and blood stasis type PD movement,And non-toxic side effects.Evaluation ofPD kidney and blood stasis type of movement disorders,Treatment group UPDRS Ⅲscore improvement rate of80%,Control group UPDRS Ⅲscore improvement rate of50%,Differences between the two groups compared to improve motor symptoms ofParkinson’s disease have significant(P<0.05),Description motor symptoms ofParkinson’s disease therapy group improved significantly better than the controlgroup efficacy,Syndromes in terms of improving the total effective rate of60%,According to the group, the total effective rate was10%,There are differencesbetween the treatment and control groups was significant(P<0.05),Descriptionmotor symptoms of Parkinson’s disease therapy group improved significantly betterthan the control group efficacy,Syndromes in terms of improving overall responserate was60%,The control group was10%,There are differences between thetreatment and control groups was significan(tP<0.05),TCM Therapeutic symptomstreatment group than the control group.Treatment group and control group beforeand after treatment baseline uric acid levels were not significantly different(P>0.05),No statistically significant.Conclusion:Through the use of experimental group have bu shen tong luoxifengFunction and add PD Western medicine basic drugs treatment can significantlyimprove symptoms of kidney and blood stasis type PD movement,More effectivethan medication alone basis PD medicine;In terms of improving TCM syndromes,experimental group have bu shen tong luoxifeng Function and add PD Westernmedicine basic drugs treatment was better than western-based medicine of PD;Andwithout any adverse drug reactions,Safe and reliable,Worthy of popularization andapplication in clinical,However, no significant difference in contrast between thetreatment group and the control group and the group before and after treatment uricacid(P>0.05),Consider small sample size,Need further study. |