Evaluation Of The Effect Of Collateral Circulation On Cerebral Ischemic Stroke In Patients With Severe Internal Carotid Artery Stenosis Or Occlusion

Objective:To explore the relationship between the status of collateral circulation and cerebral ischemic stroke in patients with severe internal carotid artery stenosis or occlusion.Methods:TCD was applied to evaluate the collateral circulation on110patients of cerebral ischemic stroke with severe internal carotid artery stenosis or occlusion. Patients were divided into5groups:ACOA group, PCOA group, OA group, combined ACOA and PCOA group,and non-collateral compensation group. The National Institutes of Health Stroke Scale (NIHSS) score was used both at admisscion and two weeks later。 The Modified Rankin score (mRS) was used at admisscion and six months later.Results:(1)TCD showed collateral patency of anterior artery communicating was43%, posterior communicating artery was35%, and ophthalmic artery was25%.(2) The scores of NIHSS and mRS were no significant difference in non-collateral compensation group before and after treatment (P>0.05).(3) The NIHSS score at two weeks and mRS score6months later were lower in combined ACOA and PCOA group,ACOA group and PCOA group Significantly than in OA group and non-collateral compensation group(p<0.05).(4)The NIHSS score was lower in combined ACOA and PCOA group than in ACOA group.Conclusion:In patients of cerebral ischemic stroke with internal carotid artery stenosis, collateral patency of anterior communicating artery was the main patency pathway. The symptoms and lesion of cerebral ischemic are associated with the patency type of Willis circle.