Comparative-study About Spirometr And Nocturnal Hypoxemia Between Patients With And OSAHS

SAHS (sleep apnea hypopnea syndrome) is defined as nasal cavity air flow arrest for more than30times during seven hour sleep per night and every nasal cavity air flow arrest is longer than10seconds or AHI is greater than5times per hour. SAHS is a common sleep apnea impediment disease, and PSG(polysomnography) is a main method for diagnosis. SAHS is divided as three types:obstructive type, combined type and central. OSAHS comprises90percent of SAHS.3%-28%adults are suffering from slight OSAHS and1%-14%are from moderate OSAHS. Prevalence rate of OSAHS among children and adolescents is1%～10%. OSAHS presents partly or totally upper airway obstruction during sleep, air flow decrease or even arrested in spite of breezing with great effort. Acute hypoxemia and hypercarbia are frequently accompanied as a result of insufficiently velar ventilation. Acute respiratory failure in sleep is another complication, multi-organ injury Call be seen after long-term and repeated attack, such as chronic respiratory failure, pulmonary hypertension, stroke, chronic cot culminate and multi-organ injury. OSAHS complicated with COPD are called OS(overlap syndrome), it is reported morbidity of which is6%-16%. Hypoxia and hypercarbia are more serious as a result of obstruction of peripheral and upper airway, ventilation dysfunction and central dysfunction, furthermore, multi-organ injury are usually seen, such as cot culminate, respiratory failure, high blood pressure and coronary heart disease.Objective:Comparetive-study between lung function and nocturnal hypoxemia in patients with OS and OSAHS.Methods:Objective To explore the difference in pulmonary function between overlap syndrome (OS) and (OSAHS) sleep apnea-hypopnea syndrome (OSAHS)patients. Methods50patients who were randomly recruited were divided into two groups, which contained25overlap syndrome patients and25patients OSAHS respectively. To compare the difference in polysomnography, pulmonary function tests and blood gas analysis.Results:(1) The lowest SaO2in the OS group were lower than that in the OSAHS group (P<0.01). Lat, AHI in OS group were higher than those in OSAHS group (P<0.01)(2) PaCO2in OS group were higher than that in the OSAHS group (P<0.01) while PaO2in OS group were lower than those in OSAHS group (P<0.01)(3) FVC℃、FEV1%and FEV1/FVC%were lower than those in OSAHS group (P <0.01)(4) AHI of two groups(OS patients and OSAHS patients) were negative correlation with data of pumlmomary function(FVC%,FEV1%predicted,FEV1/FVC%)(P<0.01)(5) LSaO? of two groups(OS patients and OSAHS patients) were positively correlation with data of pumlmomary function(FVC%,FEV1%predicted, FEV1/FVC%)(P<0.01)(6) AHI of two groups(OS patients and OSAHS patients) were negative correlation with PaO2(blood gas analysis data)(P<0.01); AHI of two groups(OS patients and OSAHS patients) were positively correlation with PaCO2(blood gas analysis data)(P<0.01)(7) LSaO2of two groups(OS patients and OSAHS patients) were positively correlation with PaO2(blood gas analysis data)(P<0.01); LSaO2of two groups(OS patients and OSAHS patients) were negative correlation with PaCO2(blood gas analysis data)(P<0.01)(8) PaO2of two groups(OS patients and OSAHS patients) were positively correlation with data of pumlmomary function(FVC%,FEV1%predicted, FEV1/FVC%)(P<0.01)Conclusion:The pulmonary function injury in the OS group was more serious than that in OSAHS group. Conclusion Hypoxemia in the night in the OS group was more obvious than that in that in OSAHS.