The Clinical Research And Long-term Efficacy Investigation For Lumbar Disc Herniation Treated By An Interspinous Device(Coflex^TM)

ObjectiveTo compare the long-term efficacy, safety and significance between lumberdiscectomy and the Coflex interspinal dynamic fixation system in the treatment oflumbar disc herniation.MethodsFrom January2009to May2013,80cases of patients with lumbar disc herniationwere enrolled in our study,37cases (male20, female17) were treated by lumberdiscectomy,43cases (male23, female20)were treated by Coflex system. Allpatients received VAS, lumbar JOA and the Owestry Disability Index assessmentpreoperative and postoperative12,24,36and48months. Surgical segmental dorsaldisc height, the ventral disc height and spinal canal area were also measured throughX-ray film and CT.ResultsThe time of follow-up in patients with lumbar disc herniation and Coflex system is(45.7±11.2) months and（46.2±10.7）months, respectively. The results of JOA were significantly higher in patients with Coflex than with lumber discectomy during thefollowed48months after surgery, Coflex system treatment also showed advances inVAS and Owestry Disability Index assessment during the followed36and12months,respectively. The results of surgical segmental dorsal disc height, the ventral discheight and spinal canal area in the last follow-up were statistically significantcompared with the preoperative results, and there is a significant difference in theabove parameters between the two groups at the last follow-up.Conclusion48months follow-up showed that patients with Coflex system had advantages inlong-term clinical efficacy compared to those with lumber discectomy, and we shouldpay attention to the indication of them and apply them for lumbar disc herniationtreatment.