Correlation Between Osteoporosis And Coronary Heart Disease In Elderly

Objective：To investigate the correlation between osteoporosis andcoronary heart disease in elderly.Method：1192hospital patients in Gerontology Department wereinclude in the study, divided into male middle-aged non-coronary heartdisease group, middle-aged coronary heart disease group, elderly non-coronary heart disease group, elderly coronary heart disease group, olderelderly non-coronary heart disease group, older elderly coronary heartdisease group and female middle-aged non-coronary heart disease group,middle-aged coronary heart disease group, elderly non-coronary heartdisease group, elderly coronary heart disease group, older elderly non-coronary heart disease group, older elderly coronary heart disease group.All of them were determined liver and kidney biochemistry, fasting plasmalipid and blood sugar, and bone mineral density in the corresponding timeperiod. Each group was divided into non-osteoporosis group, mildosteoporosis, moderate osteoporosis and severe osteoporosis. We analyzedrespectively the difference of coronary heart disease morbility between twogroups in female and male in the condition that there was no statistical difference between non-osteoporosis groups and osteoporosis group onbasic datas. By these results, we probed the comparision betweenosteoporosis and traditional risk factors of coronary heart disease. Weanalyzed respectively the difference of basic datas， hormones, boneformation and resorption markers, serum calcium and phosphate and otherelements between groups of non-coronary heart disease and coronary heartdisease.Result：(1) There was statistical difference between osteoporosisgroups and non-osteoporosis group in female on the morbility of coronaryheart disease(all p<0.05), but not in male(all p>0.05).(2) By comparing themorbility of coronary heart disease between mild osteoporosis, moderateosteoporosis and severe osteoporosis, we found that there was statisticaldifference between osteoporosis degree and the morbility of coronary heartdisease in female (all p<0.05).(3) There was statistical difference betweenfemale with non-coronary heart disease and coronary heart disease on BMI,WHR and the level of serum TG, LDL-c, UA and HDL-c in middle-agedand elderly groups (all p<0.05).(4) By comparing osteoporosis andtraditional risk factors of coronary heart disease, we found that the odd rateof osteoporosis was respectively4.187.Conclution： The relation between osteoposis and coronary heartdisease in female existed, but did not exist in male. The degree ofosteoporosis got a positive correlation with the morbility of coronary heart disease in female(p<0.05). Osteoporosis had an important rank in themorbility of coronary heart disease even exceeded traditional risk factors.