Study Of Hemodynamics Change Of Intracranial And Extracranial Vascular Of Hypertension In Different Grades

Objective:To explore characteristics and correlation of hemodynamics change of intracranial and extracranial of internal carotid artery and vertebral-basilar artery of essential hypertension. Methods:According to the the grade of hypertension,160patients with essential hypertension were divided into three groups,grade1, grade2and grade3,50cases were control group. To measure PSV, EDV, PI and RI of internal carotid artery (ICA) of extracranial segment and middle cerebral artery (MCA), anterior cerebral artery (ACA) of intracranial segment in internal carotid artery system and vertebral artery2(VA2) of extracranial segment and posterior cerebral artery (PCA), vertebral artery1(VA1) and basilar artery(BA) of intracranial segment in vertebral-basilar artery system by transcranial doppler ultrasonography(TCD) and color doppler flow imaging(CDFI) in each group, respectively. Results:With the grade of hypertension increasing, PSV and EDV were decreased,PI and RI were increased in both of Internal carotid artery and vertebral-basilar artery. PSV and EDV of internal carotid artery were decreased in grade2hypertension group, EDV was decreased, RI was increased in grade1hypertension group of vertebral-basilar artery. The PI and RI of intracranial PCA and extracranial VA2were negative correlation in grade3hypertension group of vertebral-basilar artery, the correlation of intracranial and extracranial in grade2and grade3hypertension group were positive correlation with two systems. Conclusions:The decrease of PSV and EDV were the early indicators of grade2hypertension in internal carotid artery, the decrease of EDV and increase of RI were the early indicators of grade1hypertension in vertebral-basilar artery. There were correlated in intracranial segment and extracranial segment vascular of grade2and grade3hypertension.