Analysis Of Relevant Research On Lumbar Spine BMD,Body Composition And Related Factors In Elderly Women Based On Improved QCT Measurement

Objective:To explore the using of improved quantitative CT (QCT) for measurement of lumbar spine bone mineral density(BMD) as well as the observation of physical characteristics among the ealdy women, and to analyze the relationship between the lumber BMD and the content including lumbar paraspinal muscles, fat, blood vessel calcification and serum lipids. Methods:A total of90elderly women were selected from the physical examination center who undergo exam of lumbar spine, the subjects L2-L4vertebral bone mineral density (bone mineral density, BMD) was measured by both using QCT volume scan and QCT standard measuring. Lumbar paravertebral body composition content in L2-L4the same level were measured by using post-processing software measurement QCT image, analysis of the relationship between bone mineral density of lumbar vertebrae and physical characteristics and serum lipid. Statistical analysis of paired t test, consistency analysis, Pearson correlation analysis and multiple stepwise regression analysis. Results:①There were no statistically significant difference in meanBMD value, T value and Z value by using the two measuring methods (P>0.05). BMD value and T value have high correlation with osteoporosis degree by using the two measuring methods. The correlation coefficient of BMD value and T value respectively were0.970and0.968.②In the three groups,the negative correlation was found between BMD and age (P<0.05), L2BMD, L3BMD were positively correlated with bilateral psoas, erector spinae density (r=0.233-0.301, P<0.05).While the L4BMD was positively correlated with bilateral erector spinae density and abdominal fat area.③Multiple stepwise regression analysis revealed that muscle is an importantvariable which affected the BMD,except the age. Age is the only one factor which entered the three lumbar BMD regression equation and had a negative correlation with the lumbar spine BMD.④No association was indicated between serum lipid (triglyceride, High-density lipoprotein, Low-density lipoprotein, cholesterol) and lumbar BMD. Conclusion:①The improved QCT method in measurement of bone mineral density with high accuracy, osteoporosis diagnosis efficiency.②The correlation between elderly women’s bone mineral density of lumbar vertebrae and paravertebral psoas muscle, erector spinae muscle density, abdominal fat area, age was close, apart form the impact of age, paravertebral muscle density has a greatest enfluence on bone mineral density.③No association was indicated between serum lipid and lumbar BMD. QCT scan is a more intuitive, accurate method which display spine and paraspinal body composition, can be well used to diagnosis osteoporosis.