Clinical Effect Of Trabeculectomy Combined With Mitomycin C Versus Ahmed Glaucoma Valve Implantation For Uveitic Glaucoma

Objective: To evaluate the clinical effects of trabeculectomy withMitomycin C (MMC) versus Ahmed glaucoma valve implantation in thetreatment of uveitic glaucoma.Methods: A total of60eyes of60patients with uveitic glaucoma whoreceived filtering surgery were analyzed retrospectively. All cases weredivided into two groups:31eyes in Group A were treated with MMCenhanced trabeculectomy and29eyes in Group B with Ahmed glaucomavalve implantation. Pre-and post-operative intraocular pressure (IOP),visual acuity, success rate, filtering bleb and complications were observed inthe two groups.Results: Secondary glaucoma was most commonly seen inVogt-Koyanagi-Harada syndrome (28.33%), followed by Behcet disease(21.67%) and idiopathic uveitis (15%). The intervention was effectiveevaluated by comparing the IOP (P＜0.001) pre-and post operation in eachgroup. The comparison of IOPs was significantly different at6months and final follow-up (t=2.550，P=0.014at6months; t=2.494，P=0.016at finalfollow-up). The success rate of group B was significantly higher than that ingroup A at6months and final follow-up (χ2=4.351, P=0.037at6months;χ2=5.053, P=0.025at final follow-up). There was no significant difference invisual acuity and complications between the two groups．Conclusions: Trabeculectomy combined with MMC and Ahmedglaucoma valve implantation are two effective surgical procedures in thetreatment of uveitic glaucoma. Ahmed glaucoma valve implantation showesbetter IOP control and higher mid-term success rate than trabeculectomywith MMC. It can be used as the primary procedure for uveitic glaucoma.