| Objective:Through the type2diabetes mellitus patients with atherosclerosis basic information, TCM typing, laboratory parameters and other factors, according to statistical analysis to explore the laws of diabetic patients with atherosclerosis in the distribution of syndromes, and glucose and lipid metabolism related laboratory parameters and syndromes relationships.and providing new methods for ancillary clinical treatment.Methods:50patients that met qualifying criteria for study, TCM symptom score to assess the situation of TCM symptom; and observe blood sugar, blood lipids, hemoglobin A1c(HbA1c), homeostasis model assessment of insulin resistance(HOMA-IR), Color Doppler ultrasonography and ABI and so on. According to the statistical analysis, to explore diabetes mellitus artery syndromes law atherosclerosis.Results:1. Included in the study of type2diabetes mellitus patients with atherosclerosis, patients suffering from peripheral arterial disease up to61%; Within200patients,56%had a history of hypertension,47.5%had a history of high cholesterol, Patients with carotid artery plaque account for43.5%,Coronary heart disease, stroke, abdominal aortic aneurysm and breast cancer in turn for15.5%,5%,1.5%,4.5%.2. In type2diabetic patients with atherosclerosis syndrome distribution situation,Liver and Kidney Yin Deficiency and Syndromes sputum silt each knot the highest proportion,accounted for34%and33%, respectively,followed by the spleen qi deficiency accounted for11.5%,10.5%in patients with spleen deficiency, pyrophlegm stagnation11%.3. From the course of distribution, diabetic patients with atherosclerosis early in the course of qi-based, with the growth of the course,Yin and Phlegm syndromes occur peak,Late in the course of the performance of the liver and kidney, phlegm-based.4. TCM symptoms mean from each group were compared Triglycerides distribution from low to high order of spleen deficiency syndrome <spleen qi deficiency <pyrophlegm Stagnation <liver and kidney syndrome<phlegm and blood stasis blocking collaterals.5. TCM symptoms mean from each group were compared HbAlc distribution from low to high order of spleen qi deficiency <spleen deficiency syndrome<liver and kidney syndrome<phlegm and blood stasis blocking collaterals <pyrophlegm Stagnation.6From the number of ABI and carotid plaques view, Liver and kidney syndrome and phlegm and blood stasis blocking collaterals have a highest proportion.Conclusion: 1Observing diabetic patients with atherosclerosis syndromes found Liver and kidney syndrome> sputum silt each node syndrome> spleen qi deficiency> spleen deficiency syndrome> pyrophlegm Stagnation.2. HbAlc visually reflects glycemic control in patients with blood glucose control in patients with spleen qi deficiency still, slightly lighter symptoms of complications, such as poor long-term control of blood glucose, is prone to liver and kidney, phlegm, pyrophlegm blues.3. TG reflects lipids in patients with type2diabetes is generally high, which phlegm and blood stasis, liver and kidney syndrome high blood lipids.4. ABI and carotid artery plaque distribution of TCM syndrome groups from low to high are followed:sputum silt each node syndrome> liver and kidney syndrome> pyrophlegm Stagnation> phlegm stasis syndrome> spleen qi deficiency> spleen deficiency syndrome5. The study by observing the diabetic patients with atherosclerosis syndromes proposed "liver and kidney deficiency and phlegm-stasis blocking collaterals " is main pathogenesis of diabetes mellitus with atherosclerosis, which is the ideological and theoretical treatment of type2diabetes and atherosclerosis have clinical significance. |