Radiofrequency Ablation For Barrett’s Esophagus Meta-analysis

Objective：In patients with Barrett’s esophagus (BE), radiofrequency ablation(RFA) can eradicates dysplasia and intestinal metaplasia safety and effectively. Aimed to determine the efficacy and durability of RFA for patients with BE.Methods：Through the computer retrieval pubmed, medline, CNKI, wanfangdatabase to collect information, extract the effective data, and statisticalanalysis was performed using Stata version12.0.Results：We choice7studies (3477patients) reporting efficacy,in which including4studies (540patients) had reported durability. CE-IM was achieved in84%of patients (95%CI=0.74–0.94), CE-D was achieved in85%(95%CI,0.78–0.93)and the proportion of malignant progress is (8%CI,-0.03–0.2%). After eradication, IM recurred in9%(95%CI,0.04–0.13). Esophageal stricture was the most common adverse event and was reported in11%of patients (95%CI0.04–0.18,). Conclusions：Treatment of BE with RFA have a high proportion of patients in CE-D and CE-IM, few recurrences of IM after CE-IM and have low rate of adverse events. RFA is a good choice for patients with Barrett’sesophagus.