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Distribution Of Porphyromonas Gingivalis With Type â…¡ Fimbriae In Endodontic Infections

Posted on:2015-08-01Degree:MasterType:Thesis
Country:ChinaCandidate:Y LiFull Text:PDF
GTID:2284330452967314Subject:Oral and clinical medicine
Abstract/Summary:PDF Full Text Request
Objective: This study detected Porphyromonas gingivalis fimA II genotype ininfected root canals by two different primers, aiming to reveal the distribution ofPorphyromonas gingivalis fimA II genotype in endodontic infections as well as itsassociations with the clinical symptoms and signs.Materials and Methods: Select135infected root canal samples of patients withchronic apical periodontitis. Use the PCR procedure with P. gingivalis universalprimers to identified the presence of P. gingivalis, and a couple of new fimA type IIspecific primers are used to detect the fimA type II in P. gingivalis positive samples.Finally, the results are statistically analyzed.Results: The detection rate of P. gingivalis in the apical root canal with chronicinfection is34.8%, and the dfficiency of detecting the fimA type II gene between theformer and new primers are not statistically significant (former primers:11.8%; newprimers:12.6%). The results shows that Porphyromonas gingivalis with fimA IIgenotype is related to fistula and there is no significant correlation betweenspontaneous pain, percussion pain, occlusal pain and swelling(P>0.05).Conclusion: The detection rate of P. gingivalis with fimA II genotype in the apicalroot canal with chronic infection is high (>10%), and P. gingivalis with fimA IIgenotype is related to fistula.
Keywords/Search Tags:Porphyromonas gingivalis, fimA II genotype, endodontic infections, clinical symptoms and signs
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