| Objective: Discuss the X-ray performance characteristics and clinical pathologic features of triple negative breast cancer. In order to deepen the understanding of the X-ray signs and improve the level of diagnosis in it.Methods: Collect 176 cases in triple negative breast cancer which confirmed by pathology and compare with the non-triple negative breast cancer cases that be hospitalized at the same time, in order to analysis the 105 cases X-ray manifestations and clinical pathology who met the requirements.Result:1 A total of the patients in triple negative breast cancer was 176 and the age of onset was 22-76, and the average age was 51.5. Among them there were 97(97/176,55.1%) cases on the left side and 79(79/176,44.9%) ones on the right side. Be relative to the 436 patients who in non-triple negative breast cancer over the same period,we know that the age of onset was 23-81 and the mean age was 50.9, 223 cases on the left side while 213 on the right. So there is no differences in the onset age and the prevalence of left and right side of the breast.2 121 patients who in triple negative breast cancer had the pathological results. The main pathologic types was infiltrating ductal carcinoma(62.0%).The second types were medullary carcinoma(21.5%), metaplastic carcinoma(6.6%)and other pathological types of breast cancer(9.9%).3 In this group, the X-ray manifestations of 105 cases who in triple negative breast cancer was mainly the mass shape(78.1 %).Nearly half of them had clear edge(46.3%), while similar to the benign lesions. And 24.4%(20/82)was tumor with calcification.4 There were 25 cases had calcification in this group, while 17 were infiltrating ductal carcinoma, 3 were medullary carcinoma and 5 were other types of cancer. The calcification distribution in triple negative breast cancer was mainly for regional or cluster, while the morphology was mainly for amorphous and polymorphy.5 In triple negative breast cancer, 48 cases who had infiltrating ductal carcinoma were the mass shape(75.0%,48/64). The tumor shape was mainly manifested as irregular shaped(21cases,43.8%)and round(17cases,35.4%). The edges were mainly for the clear edge( 16 cases,33.3%), stellate(15cases,31.3%) and infiltrating margin(10cases,20.8%). And 17 cases showed calcification(26.6%,17/64).While medullary carcinoma in 20 cases showing mass(83.3%,20/24). The main performance was the circular similarity(11 cases, 55%). And the edge mainly was the clear edge(16 cases, 80%). And the calcification in 3 cases(12.5%). The X-ray signs of two groups of different pathological types of the patients had differences in tumor morphology and edge(P<0.05).6 Compare with the X-ray signs in infiltrating ductal carcinoma between triple negative breast cancer and non-triple negative breast cancer, we knew that there were 82 cases(85.4%,82/96)performanced the mass shape. And it mainly manifested as irregular(55 cases, 67.1%). Edge was mainly stellate(53 cases, 67.1%).And 41 cases showed calcification(42.7%, 41/96). While Calcification mainly for the cluster and regional distribution which was malignant or suspicious for malignancy. The X-ray signs had differences in tumor morphology, edge and with or without calcification(P<0.05) while there is no differences in the distribution and morphology of calcification(P>0.05).Conclusions:1 There is no differences in the onset age and the prevalence of left and right side of the breast in triple negative breast cancer and non-triple negative breast cancer.2 The X-ray manifestations is always the circular similarity of tumor with clear edge in triple negative breast cancer, among them the medullary carcinoma is more likely show as benign lesions than that in infiltrating ductal carcinoma.3 The calcification probability is lower in triple negative breast cancer than that in non-triple negative breast cancer, and the calcification form is mainly as suspicious for malignancy and malignant.4 The signs of malignancy is more less in triple negative infiltrating ductal carcinoma than in non of that. |
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