| Purpose:Craniocerebral injury accounts for the second place in trauma, which with features of high incidence, quick change, complex clinical menifestations. Currently, Glasgow coma score(GCS) was the main basis of condition evaluation and prognosis of craniocerebral trauma, but in clinical practice, GCS can only reflect the state of consciousness and lack of comprehensive condition evaluation and prognosis judgment. Therefore, it is significant to find other simple, reliable and valuable monitor indicators to make up for the inadequacy of GCS. This research aims at observing dynamic change of serum glucose, lactic acid, and CRP of acute craniocerebral trauma patients,meanwhile,analyzing and sumiting its clinical significance.Methods:Randomly select 50 patients with acute craniocerebral injury in our hospital, all patients were divided into light group (13 cases), medium group (21 cases), heavy group (16 cases) according to the Glasgow coma score(GCS) when they admitted to hospital. In addition,30 cases of healthy physical examination as normal control group. The dynamic changes of Serum glucose, lactic acid and the CRP of craniocerebral injury patients were observed when in 1 d,3 d,7 d and 14 d, then a statistical analysis was made of the result of the above.Results:The levels of serum glucose,lactic acid and CRP of craniocerebral injury at 1 d,3 d,7d and 14d, craniocerebral injury group were significantly higher than that of normal control group, which has statistical significance (P< 0.05); The levels of serum glucose and lactic acid of craniocerebral injury at 1 d,3 d,7d and 14d,medium group was significantly higher than that of light group, which has statistical significance (P< 0.05); The levels of CRP of craniocerebral injury at 1 d,3 d,7d and 14d,medium group was significantly higher than that of light group, which has statistical significance (P< 0.01); The levels of serum glucose, lactic acid and CRP of craniocerebral injury at 1 d,3 d,7d and 14d,heavy group was significantly higher than that of light group and medium group, which has statistical significance (P< 0.05).Conclusions:The serum glucose, lactic acid and CRP levels of acute craniocerebral injury patients are closely linked with the degree of patients’conditions. The more severe craniocerebral injury degree, the higher serum glucose, lactic acid, CRP levels. Therefore, in clinical, patients’ serum glucose, lactic acid, CRP levels can act as important indicators,which are used to evaluate the degree of acute craniocerebral injury condition and prognosis.This also plays an important role in making a reasonable and feasible scheme. |
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