Further Explore The Correlation Between Salivary Amylase Activity Ratio In Combination With The Spleen In Patients With Specific Symptoms

ObjectiveThis article has collected ancient and modern literature on discussion of Spleen Deficiency. Summarized the theoretical basis, clinical applications, and modern medical research of spleen deficiency syndrome associated with various diseases, and as a theoretical basis, explore the spleen in patients with chronic gastritis before and after the treatment of superficial "salivary amylase activity ratio" changes its combination of clinical symptoms to improve relevance. Clinical epidemiology, signs and symptoms related mathematical statistics, the use of multiple linear regression statistical analysis of the intrinsic links between symptoms and signs of chronic superficial gastritis and Spleen Deficiency Syndrome.This study is the micro indicators syndromes in medicine research applications, in order to further achieve microscopic spleen deficiency syndrome to provide new ideas.Methods1. Literature:Researching, analyzing data, research progress and salivary amylase activity between spleen deficiency syndrome were consolidated and summarized on.2. Clinical studies:All patientsTraditional Chinese Medicine and stomach disease outpatient clinic, doctors diagnosed as chronic superficial gastritis, TCM eligible patients Spleen Deficiency Syndrome. Develop "spleen deficiency syndrome four diagnostic Registration Form" detailed records of patients before and after treatment of four diagnostic information, and to quantify the symptom score. By XiangshaLiujunzi after treatment, the ratio of salivary amylase activity was observed before and after treatment in patients with spleen and cluster analysis, multiple linear regression analysis method, correlation ratio of salivary amylase activity Spleen Deficiency main symptom combinations.Results1. Cluster analysis:Spleen in patients with abdominal distention or fullness after eating, loss of appetite and heartburn symptoms three relatively close to nature, And the relationship between the ratio of activity of salivary amylase closer than other symptoms.2. Correlations. Multiple linear regression analysis showed:Relationship salivary amylase activity ratio changes and clinical symptoms are not uniform single spleen, But with the spleen symptoms abdominal distention or fullness after eating, loss of appetite and heartburn, epigastric pain, belching combination of the symptoms there is a certain correlations. Salivary amylase activity ratio and abdominal distention or fullness after eating is positively correlated with loss of appetite, heartburn, epigastric pain, belching a negative correlation. And after treatment, the symptoms generally return results in salivary amylase activity ratio is higher than after treatment (pre-treatment R2= 81.4%, after treatment R2= 70.4%).4. Before and after treatment comparison:After XiangshaLiujunzi treatment, all patients with spleen deficiency symptoms were significantly improved (pre-treatment total score 15.33+5.84, after treatment,4.67 ± 3.48, P = 0.000), A significant increase in salivary amylase activity ratio (before treatment 0.60 ± 0.15,0.91 ± 0.28 after treatment, P= 0.000).Conclusions1. Spleen in patients with abdominal distention or fullness after eating, loss of appetite and heartburn symptoms three relatively close to nature, and the relationship between the ratio of activity of salivary amylase closer than other symptoms.2. Before treatment and after treatment in patients with salivary amylase activity spleen ratio of appetite, heartburn, epigastric pain, belching linear negative correlation, Tip preliminary salivary amylase as a digestive enzyme digestion and absorption function is the function of the spleen closely linked.3. Relationship changes the ratio of salivary amylase activity and clinical symptoms are not uniform single spleen, but with the spleen symptoms abdominal distention or fullness after eating, loss of appetite and heartburn, epigastric pain, belching, there is a certain combination of the symptoms correlation, In this combination, the ratio of salivary amylase activity and abdominal distention or fullness after eating was positively correlated with loss of appetite, heartburn, epigastric pain, belching negatively correlated, suggesting that salivary amylase activity ratio decreased to reflect the spleen deficiency syndrome to the virtual main symptoms. Clinical syndromes are often mixed with the actual situation is more common, and therefore in this study deficiency mixed or standard real symptoms, the salivary amylase activity decreased ratio does not even have cases of elevated.4. After Jianpiyiqi Recipe XiangshaLiujunzi treatment, patients salivary amylase activity ratio was increased compared with the previous treatment, clinical symptoms improved, which also proved the existence of the ratio between salivary amylase activity decreased with Spleen Deficiency close Contact.