The Study Of Modern Literature And Clinical Cure Law By Using Treatise On Febrile Disease Classical Prescription To Treat Pneumonia

ObjectiveOn the basis of six-meridian syndrome differentiation theory, search the literature about the modern use of Treatise on Febrile Disease classical prescription of treatment of pneumonia. Build a literature database about using modern TCM classical prescription to treat pneumonia, Through the literature research, describe the modern application of Treatise on Febrile Disease classical prescription of traditional Chinese medicine by the profile of the treatment of pneumonia, provide ideas for clinical diagnosis and treatment of pneumonia.By using prospective clinical observation methods, this subject is performed on cases of patients with mild-to-moderate pneumonia. According to the theory of six-meridian syndrome differentiation, collecte the patient’s four diagnostic information, and make a preliminary analysis of the classification of pneumonia six-meridian differentiation syndromes and the four characteristics. To discuss justification of six-meridian differentiation characteristics, clinical characteristic and diagnosis and treatment, and provide the reference of the clinical diagnosis and treatment of pneumonia for preliminary six-meridian differentiation standards and further research.Methods1.Modern literature research of using Treatise on Febrile Disease classical prescription to treat pneumoniaRetrieving CNKI by computer, Collect the literature of using the Treatise on Febrile Disease classical prescription to treat the pneumonia. Using content analysis and dose of analysis, filter the literature and extract the data. Build a database of modern TCM classical prescription for the treatment of pneumonia.Adopt the method of descriptive study, describe the modern application of Treatise on Febrile Disease of traditional Chinese medicine by the party profile for the treatment of pneumonia. And to sort the modern literature, summarizes the drug laws.2.Prospective clinical studyBy using prospective clinical observation methods,this subject is performed on 100 cases of patients with mild-to-moderate pneumonia. According to the theory of six-meridian syndrome differention,adopt the original classical prescription,collect the patient’s four diagnostic information, make a preliminary analysis of classification of pneumonia six-meridian differentiation syndromes and the four characteristics.To witness type group, compares the difference of clinical data and the demographic data of each card type. Type justification of six-meridian differentiation syndromes characteristics, clinical characteristic and diagnosis and treatment.Results:1. Modern literature research of using Treatise on Febrile Disease classical prescription to treat pneumonia(1) literature bibliometric analysisCNKI retrieval of literature Include 60 classical prescriptions, involve 816 articles. According to the results of runs test, there is an upward trend in the total number of article of using the classical prescription to treat pneumonia (P<0.05).Discusses literature, case reports, the number of RCT and unRCT literature references in general are on the rise (P<0.05), the rising trend of RCT literatures in recent years is obvious.(2) literature content analysisThe modern use of pneumonia has a wide range. The most commonly used formula is maxingshigan decoction, followed by xiaoxianxiong decoction, zhenwu decoction, baihu decoction, zhuyeshigao decoction xiaoqinglong decoction, baihujiarenshen decoction, chenqi decoction, lizhong decoction, dachengqi decoction, gegenhuangqinhuanglian decoction, banxiaxiexin decoction, sinisan decoction, zhizichi decoction, linguizhugan decoction, sinitang decoction, xiaochaihu decoction, etc. The statistical in the class of the most commonly used for mahuangtangleifang(295,30.38%), followe by chengqitangleifang(171,17.61%), followed by baihutangleifang, lizhongtangleifang, zafangleifang, sinitangleifang, xiexint angleifang, chaihutangleifang, gegentangleifang, zhizitangleifang, guizhitang leifang, wuliangsanleifang.Modern TCM uses after the treatment of pneumonia, treatment with the original party of 273, accounting for 28.12%; Toadd and subtract the original party for a total of 698, accounting for 71.88%; Combined with the classical prescription of 89, accounting for 9.17%, timeliness 333, accounting for 34.29%, other add and subtract accounts for 276, accounting for 28.42%.Modern Chinese medicine commonly used by the classical prescription in the treatment of pediatric pneumonia, followed by adults, middle-aged and old pneumonia. The type of pneumonia, most about the document of atypical pneumonia (80,8.24%), followed by, Bronchial pneumonia, severe pneumonia, mycoplasma pneumonia, lobar pneumonia, heart failure,pneumonia and asthmatic pneumonia. 2. Preliminary research on six-meridian differentiation syndromes of treatment mild-to-moderate pneumonia(1) Six-meridian syndrome type distribution100 patients of six-meridian syndrome type to the card type of 44 cases, double or more meridian syndromes has 56 cases.100 patients can be divided into 5 groups:taiyangshaoyinhebing group (32 cases), shaoyin syndrome group (23 cases), taiyin syndrome group (17 cases), taiyangtaiyinhebing group (16 cases), the other group (12 cases, includingshaoyangyangminghebing, taiyinyangminghebing, shaoyang syndrome, taiyang syndrome, Yangming syndrome, shaoyinjueyinhebing, taiyangshaoyanghebing, shaoyinyangminghebing). The most common of shaoyin syndrome of 100 cases (69 cases), followed by the taiyin syndrome, taiyang syndrome (both 44 cases), yangming syndrome, shaoyang syndrome, jueyin syndrome is relatively small. By system clustering analysis results suggest shaoyin certificate, taiyang the certificate for a class, taiyin certificate for a class, yangming, shaoyang syndrome, jueyin together for a class.(2) Different six-meridian syndrome prescriptionTaiyangshaoyinhebing in primary prescription for the most common is tongmaisini decoction, second pogejiuxin decoction, biantongxiaoqinglong decoction, guizhijiafuzi decoction, mahuangfuzixixin decoction,etc. Shaoyin syndrome party primaries for most pogejiuxintang, secondly also sinitang, yinhuotang, wenshibentuntang; taiyin synodme in the primary side up to lizhongtang, or banxiaxiexin decoction; taiyangtaiyinhebing use guizhirenshentang, or choose lizhongtang,add to some to help nourish. Prescription with five types of syndrome types of correspondence analysis, the result indicates shaoyin syndrome, taiyangshaoyin syndrome two kinds of type commonly used sinitang subtraction, mahuangfuzixixintang subtraction, pogejiuxintang, biantongxiaoqinglong decoction, yinhuotang; The taiyin syndrome and taiyangtaiyin two syndrome types commonly used lizhongtang, reduce, or banxiaxiexin soup; Other syndrome types commonly used chaihuleifang,xiaoxianxiong decoction, gegentang.(3) Compare different six-meridian syndrome group general situation Different six-meridian syndrome group sputum culture scores by Fisher’s exact probability method, the results suggest difference was statistically significant (P=0.012<0.05), discharge rating by the rank and inspection, results suggest difference was statistically significant (x2=11.001, P=0.027<0.05); The rest of the project such as gender, history of smoking, drinking, history of allergies, cause, course, physical examination project, auxiliary examination projects by comparing differences had no statistical significance (P>0.05).(4) Different philosophical schools of traditional Chinese medicine (TCM) syndrome group symptoms distribution and score moreBad cold, cough, cough up phlegm, stomach pain, dry tongue coating and greasy tongue coating, each string of arteries and veins and arteries and veins and moist from right certificate type grouping comparison difference was statistically significant (P<0.05), cough, cough up phlegm, cold evil score and TCM symptoms overall comparative differences between groups was statistically significant (P<0.05); More than four diagnostic data, shortness of breath, fever, sweating, diet, and tongue veins comparing differences between group had no statistical significance (P>0.05).Conclusion1.The modern literature metrology analysis for the treatment of pneumoniaBy the treatment of pneumonia literature, there is an upward trend in the total number of article discusses literature, case reports, the number of RCT and unRCT literature references in general is on the rise, RCT literature rise significantly in recent years.The modern use of pneumonia has a wide range. The most commonly used formula is maxingshigan decoction, followed by xiaoxianxiong decoction, zhenwu decoction, baihu decoction, zhuyeshigao decoction xiaoqinglong decoction, baihujiarenshen decoction, chenqi decoction, lizhong decoction ect.By using the original and modern Chinese medicine decoction for the treatment of various types of pneumonia, such as atypical pneumonia, bronchial pneumonia, severe pneumonia, mycoplasma pneumonia, lobar pneumonia, pneumonia, heart failure and asthmatic pneumonia.2.Preliminary research on six-meridian differentiation syndromes treatment mild-to-moderate pneumoniaThe common syndromes of pneumonia is taiyangshaoyin syndrome, shaoyin syndrome, taiyin syndrome, taiyangtaiyin syndrome. Shaoyin syndrome, taiyangshaoyin syndrome two kinds of type commonly used sinitang subtraction, mahuangfuzixixintang subtraction, pogejiuxintang, biantongxiaoqinglong decoction, yinhuotang; The taiyin syndrome and taiyangtaiyin two syndrome types commonly used lizhongtang, or banxiaxiexintang; Other syndrome types commonly used chaihutangleifang, xiaoxianxiongtang, gegentang.The taiyangshaoyin syndrome appear cold evil more than his card, evil cold in his card weight; Taiyangshaoyin syndrome, shaoyin cough more than his card, cough score higher, cough heavier; The taiyangshaoyin, shaoyin syndrome appeared cough up phlegm, shortness of breath from his card. Thetaiyang shaoyin syndrome of TCM symptoms the highest total.score, the illness is his certificate. Coating on the tongue is dry, respectively, in the shaoyang syndrome, yangming syndrome, shaoyin, there are both cold syndrome, heat syndrome. Taiyangshaoyin syndrome and shaoyin ayndrome appeared string pulse frequency more than other syndrome. The pneumonia patients with Taiyin ayndrome often appear greasy coating on the tongue, pulse condition and moist.