The Clinical Observation In Treating Spleen Deficient Patients With Pure HPV Infection Or HPV Infection With CIN â…  With Changed Wandai Decoction

ObjectiveThis study based on the advantages of traditional Chinese medicine, Chinese medicine characteristics and role, and severely, to seek effective oral medicine prescriptions, raise the overcast rate of spleen deficient patients with pure HPV infection or HPV infection with CIN I, trying to find a method of effective intervention HPV cloudy in time to prevent the further development of the disease, reduce the morbidity and mortality of cervical invasive cancer, improve the prognosis of patients, make up for the inadequacy of western medicine treatment of virus infectious diseases.MethodCollect aged 18 to 50, the first affiliated hospital of guangzhou university of TCM doctor of gynecological clinic patients, diagnosed with HPV infection or HPV infection CIN I, at the same time for patients with spleen deficiency syndrome differentiation of traditional Chinese medicine as research object, were randomly divided into treatment group and control group. Treatment group use changed Wandai decoction to be taken orally and vaginal local use bao fu Kang Shuan, from menstrual clean 3 days on consecutive days for one period of treatment, one menstrual cycle in a period of treatment, treatment course, three cycle 4 menstrual clean 3 days after the evaluation of curative effect; The local administration of the control group only, usage and treatment group. Observation indexes including HPV, clinical symptoms and syndromes. Using SPSS17.0 system data processing software processing, the final objective evaluation of clinical curative effect.ResultSingle HPV infection therapy treatment group effective rate was 33.3%, multiple infection effective rate was 60%, total effective rate was 40%; Single HPV infection control group treatment effectiveness 16.7%, multiple infection effective rate was 40%, total effective rate 24%; On HPV treatment effect, whether single or multiple HPV infection, HPV infection in the two groups of HPV infection or HPV infection with CIN Ⅰ patients HPV overcast all have certain effect, but there was no statistically significant difference in the two groups, suggests that on the basis of using bao fu Kang Shuan, after using changed Wandai decoction to be taken orally and does not further improve patients HPV turn rate.Clinical curative effect of treatment group 0%, recovery were 20%,55%, effective invalid 25%, total effective 75%; TCM syndrome score 5% recovery, 25% had marked effect,60%,10% is invalid, the total effective 90%. Control group clinical curative effect of healing by 0%,6% had marked effect,24%, 70% is invalid, the total effective 30%; TCM syndrome score 0% recovery,0% had marked effect,41%,59% is invalid, the total effective 41%. In clinical symptom curative effect, symptom score of traditional Chinese medicine, the treatment group and control group differences were statistically significant before and after the treatment, show that two groups in improving clinical symptoms, syndromes have effect; And differences between the two groups was statistically significant, which indicates that the effect of treatment group is better than the control group, which uses bao fu Kang Shuan basis, add the changed Wandai decoction to be taken orally, can further improve the patient’s clinical symptoms and syndromes rate.No adverse events occurred in both groups. Conclusion Both treatment group and control group, the treatment for HPV all have certain effect, but on the basis of using bao fu Kang Shuan, after using changed Wandai decoction to be taken orally cannot be further increase the rate of patients with HPV overcast (whether a single or multiple HPV infection). Both treatment group and control group, the clinical symptoms, syndromes are improved, and the use of bao fu Kang Shuan combined with traditional Chinese medicine on the basis of the changed Wandai decoction to be taken orally, can further improve the patient’s clinical symptoms and syndromes rate, clinical curative effect is positive, at the same time, the clinical application are safe.