Objective : To observe the traditional Chinese medicine(kidney huoxue soup(the)/Tong Jing Ning party and subtract) staging treatment of kidney and blood stasis type of recurrent ovarian endometriosis(after the artful bursa for short) of clinical efficacy; TCM periodic therapy on kidney deficiency and blood staging type of artful capsule in patients with clinical symptomsã€artful OEC volume change and its effect on Em Ab, CA125 in serum.Methods:Outpatients were collected 60 cases diagnosed with kidney and blood stasis type complete cases of endometriosis patients, randomly divided into two groups,treatment group 30 cases kidney huoxue soup to take orally the party after menstruation,menstrual internal and from party Tong Jing Ning party; Control group 30 cases in the menstruation after taking mifepristone treatment of western medicine, two groups of course are three menstrual cycles. By observing the two groups before and after treatment in patients with clinical symptoms improved, artful bursa size change and influence on serum Em Ab, CA125, discuss the possible mechanism of action, and provide theoretical basis for Chinese medicine treatment of the disease.Results:1.The clinical curative effect comparison Treatment of three menstrual cycles and discontinuation after three months, the treatment group in the treatment of kidney and blood stasis type of recurrent artful bursa comprehensive curative effect of the total effective rate was 93.34%, markedly effective rate was 56.67%; The control group total effective rate was 73.34%, the efficacy of clinical comprehensive markedly effective rate was 26.67%. The comprehensive efficacy of two groups total effective rate was significantly difference(P < 0.05),markedly effective rate of the two groups have significant difference(P < 0.01).Treatment group in the treatment of kidney and blood stasis type recurrent artful bursa syndromes curative effect of the total effective rate was 96.67%, markedly effective rate was 66.67%; Control group of syndromes curative effect of the total effective rate was76.67%, markedly effective rate was 33.33%, two groups of TCM syndrome total effective curative effect more significant difference(P < 0.05), two groups of traditional Chinese medicine syndrome curative effect markedly effective rate comparison has the extremely significant difference(P < 0.01). The treatment group in the treatment of kidney and blood stasis type of recurrent artful bursa primary symptom curative effect of traditional Chinese medicine the total effective rate was 93.33%; Control the primary symptom of traditional Chinese medicine efficacy of the total effective rate was 66.67%,two groups of primary symptom curative effect of TCM total effective more significant difference(P < 0.01).2.The two groups before and after treatment of TCM syndrome and the primary symptom integral comparison Treatment of three menstrual cycles and discontinuation after three months, the treatment group and control group was compared with the TCM syndrome integral are falling, the treatment group were extremely significant difference(P < 0.01), the control group significant difference(P < 0.05); Drug withdrawal syndromes was treatment group after march integral compared with control group there were significant differences(P < 0.05). Treatment group march after discontinuation of TCM syndrome integral value than recovered after treatment in March, but there was no statistical significance(P > 0.05) difference comparison.Treatment of three menstrual cycles and discontinuation after three months, the discontinuation of treatment group was decreased, the primary symptom integral have extremely significant difference(P < 0.01), the control group compared with before treatment, the primary symptom integral in addition to the lumbar debility integral has no statistical significance(P > 0.05), decrease in other primary symptom integral, there are significant differences(P < 0.05); Withdrawal after march TCM primary symptom integral treatment group compared with control group compared with significant difference(P < 0.05). March after discontinuation of treatment group recovered after primary symptom score than the treatment of traditional Chinese medicine in March,but there was no statistical significance(P > 0.05) difference comparison.3. The two groups after treatment serum CA125 value, average artful bursa size comparison Treatment of three menstrual cycles and discontinuation after three months, the treatment group patients serum CA125 values down, compared with before treatment with significant difference(P < 0.01); Control group compared with before treatment,there are obvious difference(P < 0.05), and compared differences between group significantly(P < 0.05), compared with before treatment, the treatment group than the control group decreased significantly. Treatment group of average artful bursa shrink significantly than before treatment, there is a very significant difference(P < 0.01), the control group compared with before treatment, there is significant difference(P < 0.05);And the comparison between groups had significant difference(P < 0.05); Compared with before treatment, the treatment group than the control group to shrink significantly.4. The rate of positive of antibody of membrane resistance to compare the two groups after treatment Treatment of three menstrual cycles and discontinuation after three months, the treatment group resistant lining antibody positive rate was 23.33%, compared with before treatment significantly decreased; Control group patients with endometrial antibody positive rate was 70.00%, compared two groups was very significant difference(P < 0.01); Compared with the rate of positive of antibody of membrane resistance before treatment, the treatment group than the control group significantly lower.Conclusion:From kidney invigorate the soup with Tong Jing Ning party stage treatment of kidney and blood stasis type of recurrent ovarian endometriosis has obtained more satisfactory clinical efficacy. The traditional Chinese medicine(TCM) therapy in stages can obviously improve the kidney and blood stasis type of recurrent ovarian endometriosis patients’ clinical symptoms, alleviate the degree of dysmenorrhea,decrease CA125 and Em Ab were positive values, the volume of a narrow artful bursa.Studies suggest that cyclical therapy to treat the disease of traditional Chinese medicine is an effective method, can improve blood circulation, regulate the body’s immune function, so as to control the growth of ectopic endometrium, promote ectopic lesions absorption and clinical curative effect. |