Effect Of Chuju Polysaccharides On Health Protection

Polysaccharides is a common ingredient in plants, studies show that polysaccharides have effects of enhancing immune function, anti-aging and antioxidant,and has small toxicity and side effect. Chuju is a commonly used chinese medicine in anhui province chuzhou city,and contains flavone, polysaccharides, aetherolea, amino acids and oligoelement.This study is to explore the effect of anti-fatigue,enhancing hypoxia tolerance, antioxidant and increasing immune function on chuju.Firstly the mice was used to observe the effect of anti-fatigue and enhancing hypoxia tolerance.60 male mice were randomly divided into control group,HONGJINGTIAN gelatin capsule group and chuju polysaccharides high-dose,middle-dose,low-dose group,12 mice in each group,all mice were administered by oral administration,once a day for 5 consecutive days,effect of chuju polysaccharides on loaded-swimming time,blood lactic acid(BLA),blood urea nitrogen(BUN) and hepatic glycogen(HG),respiration frequency,respiration maintenance time,oxygen deficiency survival time were observed in mice. Results show chuju polysaccharides could significantly prolong the loaded-swimming time,decrease the content of BLA and BUN,increase the the content of HG, increase respiration frequency,prolong respiration maintenance time and oxygen deficiency survival time comparing with control group.Which confirm that chuju polysaccharides has the effect of anti-fatigue and enhancing hypoxia tolerance.Aged mice was used to observe the effect of antioxidant activities and increasing immune function.60 aged mice were randomly divided into control group,YUPINGFENGSAN group and chuju polysaccharides high-dose,middle-dose,low-dose group,12 mice in each group,all mice were administered by oral administration,once a day for 5 consecutive days,superoxide dismutase(SOD),glutathione peroxidase(GSH-Px) and malondialdehyde(MDA) in serum and liver, carbon clearance index and phagocytosis index,thymus index and spleen index,serum immune globulin were observed in aged Mice.Results show that chuju polysaccharides could significantly increase the activities of SOD and GSH-Px in serum and liver,decrease the content of MDA in serum and liver,enhance carbon clearance index and phagocytosis index,increase spleen index and thymus index,enhance the content of immunoglobulin G(IgG) and immunoglobulin M(IgM) in serum comparing with control group.Which confirm that chuju polysaccharides has the effect of antioxidant and increasing immune function.