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Systematic Evaluation About Treatment Of Traditional Chinese Medicine Compound About Phlegm And Blood Stasis Type Coronary Heart Disease Angina Pectoris

Posted on:2015-11-17Degree:MasterType:Thesis
Country:ChinaCandidate:W Y ZhengFull Text:PDF
GTID:2284330467451120Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Purpose: Adopt the method of evidence-based medicine; assess the effectiveness of thecompound Chinese medicine treatment of phlegm and blood stasis type of coronary heart diseaseangina pectoris. Provide a more scientific basis of the Chinese medicine dialectical treatment ofcoronary heart disease (CHD).Method: According to international Cochrane collaboration system evaluation method,search, collect and sort electronic database manually about the literature of traditional Chinesemedicine compound treatment of phlegm and blood stasis type of coronary heart disease (CHD)randomized controlled study published in December2013. Choose three literature assess or qualityassessment into all of the documents and use Rveman5.2Meta-analysis.Result:25clinical research, total sample2403cases were conformed to the standard. All ofthem are randomized controlled trial and Chinese literature. Consolidated statistics the Effect ofclinical comprehensive efficacy, electrocardiogram improvement, angina pectoris attack throughMeta-analysis. Evaluate25researches relating to the clinical curative effect. RR1.22,95%CI[1.18,1.27],P<0.00001. Evaluate19researches about improving Electrocardiogram (ECG) situation, RR1.33,95%CI[1.25,1.43],P<0.00001. Assess5researches about Nitroglycerin stopped reductionrate, RR1.28,95%CI [1.09,1.50],P<0.00001. Assess3researches about Frequency of anginapectoris attack, WMD-1.41,95%CI [-2.05,-0.77],P<0.00001.Assess3researches about Durationof angina attack, WMD-1.48,95%CI [-3.93,-0.97],P=0.24. Evaluate6researches about Lowdensity lipoprotein, WMD-1.48,95%CI[-3.93,-0.97],P<0.00001. Assess5researches about Highdensity lipoprotein cholesterol (HDL-C), there is no statistical significance between the treatmentgroup and control group. Analyze the sensitivity combined effect of triglycerides and cholesterol.Shows the result is unstable.Conclusion: Traditional Chinese medicine compound treatment shows the better clinicalcurative effect about phlegm and blood stasis type coronary heart disease (CHD) and anginapectoris than the pure western medicine treatment. Improve the electrocardiogram ischemia, lipidmetabolism effectively. Reduce the attack frequency of angina pectoris. Shorten the anginapectoris attack time. But the research methodological quality is low, we need to include morehigh-quality randomized controlled trials to provide more objective basis for Chinese medicine intervention in coronary heart disease (CHD).
Keywords/Search Tags:Coronary atherosclerotic heart disease, Stable angina pectoris, Phlegm andblood stasis, randomized controlled trial, Meta-analysis
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