| Objective:To evaluate the effect of comprehensive intervention on patients with high blood pressure ordyslipidemia in Kazakh or Uygur, and put the forward reasonable foundation for the effect ofcomprehensive in rural areas of the remote poverty of minorities.Methods:1. With cluster random sampling, the subjects were selected the permanent residents who is the Kazakhor Uygur and older than18years in Xinjiang(Xinyuan,Yili;Jiashi,Kashi) as baseline survey of the object.2. Using the way of home visit to collect information related to the questionnaire, physical examination andblood specimen collection, and serum total cholesterol (TC), triglyceride (TG), low density lipoproteincholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), fasting plasma glucose (FPG) weredetected with OLYMPUS2007automatic biochemical analyzer. The high blood pressure and dyslipidemiawere selected by the diagnostic criteria for metabolic syndrome made by International Diabetes Federationin2005. According to hypertension with dyslipidemia or not, the cases were split into2groups,thehypertension group and the hypertension with dyslipidemia group. The follow-up survey were carried outfrom2011to2012regularly, it was include strengthened education, distributed drugs freely, collectedfollow-up table information, physical examination and collection of blood, blood biochemical testscompleted. Outcome survey was used the same way to visit and had the same content.3. All statistical analyses were performed using the SPSS17.0statistical software. Normal distribution datawas described as (x±s),the measurement data between the two groups were compared with t test; repeatedmeasurement data was used to be analyzed by the ANOVA for repeated measurement data; count data wasused to compare the rate of Pearson χ2test, and trend Pearson χ2test.Results:1. In baseline survey, we selected963cases with high blood pressure or dyslipidemia, three years laterthere were843cases behind, the follow-up rate was87.5%; people with high blood pressure were604in2010, there were73people lost, the follow-up rate was87.9%, the follow-up rate of group that people hashigh blood pressure and dyslipidemia was86.9%.2. After comprehensive intervention, the scope of lower blood pressure of the high blood pressure inintervention group was13.76/7.94mmHg, it’s significant higher than the control group (3.16/2.27mmHg),P<0.001.In intervention group, people with high blood pressure and dyslipidemia had been better, theirscope of lower blood pressure was3.48/3.24mmHg,it is higher than the control group’s. And their TG、TC、LDL-C were decreased0.15mmol/L、0.42mmol/L、0.36mmol/L, the concentration of HDL-C was grownup0.14mmol/L, all of the lipids were better than the control group’s.3. In2012, the control rate of high blood pressure of the intervention group (44.6%) is obviously higherthan the control group (32.2%), P=0.001. The control rate of people who both have high blood pressure anddyslipidemia in the intervention group is30.72%,the control group is25.37%(χ2=1.716，P=0.633); the control rate of the blood pressure is decreased when the blood pressure levels is higher.4. After intervention, the blood pressure level classification was statistical significance between theintervention group and control group patients with high blood pressure or both have high blood pressureand dyslipidemia, the proportion of first, secondary, third level hypertensive patients decreased,and thenormal person increased significantly.5. Compare with the baseline data, the level of knowledge(K),attitude(A)and behaviors(B)were improvedsignificantly in the intervention group. There were different increases of the level of KAB the averagescores between the intervention group and the control group, the scores of knowledge, attitude, behaviorsand the total increased from0.24,0.16,0.12and0.52to3.27,2.39,0.56and6.22.Compare with the controlgroup, the knowledge, attitudes and behavior (KAP) of hypertension in the intervention group arehigher(P<0.05).Conclusion：By carrying out the comprehensive intervention of health education and drug treatment over3years,we completed the effects of combination intervention of small dose of drugs and health education are well,and the program could be used in rural areas of minorities. The comprehensive intervention is effective andpracticable, which can be able to conduct to control and reduce their BP level, increase the control rate andthe level of KAB, and to improve health and life-quality finally. |
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