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Prognosis Evaluation Of Narrow Band Imaging Guided Transurethral Resection Of Bladder Tumor

Posted on:2016-02-26Degree:MasterType:Thesis
Country:ChinaCandidate:B WangFull Text:PDF
GTID:2284330467499002Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: To investigate the clinical value of narrow band imaging guidedtransurethral resection of bladder tumor(TURBT) decreasing the recurrence rate ofnone-muscle invasive bladder cancer.Methods: Retrospectively analysis245patients initial diagnosed as bladder tumorand underwent TURBT at China-Japan union hospital of Jilin university fromSeptember2013to June2014.All the245patients were confirmed as none-muscleinvasive urothelial carcinoma by postoperative pathology. The245patients weredivided into two group:147in white light guided transurethral resection group(groupa) and98in narrow-band imaging guided transurethral resection group(group b).Thefollow-up periods were6.8-15.3months. The total recurrence and the recurrence ofparticular pathological grade, stage, tumor number(single or multiple), tumorvolume(maximum diameter of tumor over or below3cm) was observed and comparedbetween the two groups.Result:1. The total recurrence rate of group b is lower than group a, which showsstatistically significant difference(X2=6.880, p<0.05).2. The recurrence rate of high-grade urothelial carcinoma cases of group b is lowerthan group a, which shows statistically significant difference(X2=6.048, p<0.05), andthe recurrence rate of low-grade urothelial carcinoma cases of group b is lower thangroup a, which doesn’t show statistically significant difference(X2=1.057, p>0.05).3. The recurrence rate of Ta tumor cases of group b is lower than group a, whichdoesn’t show statistically significant difference(X2=3.233, p>0.05), and the recurrencerate of T1tumor cases of group b is lower than group a, which shows statisticallysignificant difference(X2=4.148, p<0.05).4. The recurrence rate of single tumor cases of group b is lower than group a, whichshows statistically significant difference(X2=4.179, p<0.05), and the recurrence rateof multiple tumors cases of group b is lower than group a, which also showsstatistically significant difference(X2=4.623, p<0.05). 5. The recurrence rate of maximum diameter of tumor over3cm cases of group b islower than group a, which shows statistically significant difference(X2=6.617,p<0.05), and the recurrence rate of maximum diameter of tumor below3cm cases ofgroup b is lower than group a, which doesn’t show statistically significantdifference(X2=1.058, p>0.05).Conclusion:1. Narrow band imaging guided TURBT can decrease the recurrence of bladdertumor rate comparing to white light guided resection.2. Narrow band imaging guided transurethral resection of high-risk bladdertumor(high-grade urothelial carcinoma, stage T1, multiple tumors, maximumdiameter of tumor over3cm) can decrease more recurrence rate of bladder tumor thanlow-risk(low-grade urothelial carcinoma, stage Ta, single tumors, maximum diameterof tumor below3cm) comparing to white light guided resection.3. For high-grade urothelial carcinoma, stage T1, single or multiple tumors,maximum diameter over3cm tumor, narrow band imaging guided TURBT candecrease the recurrence rate of bladder tumor comparing to white light guidedresection.
Keywords/Search Tags:narrow banding imaging/NBI, bladder tumor/cancer, recurrence
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