Distribution And Drug Resistance Of Pathogens Contributing To Lower Respiratory Tract Infections In The Department Of Respiratory Medicine

Background and Objective:Bacterial infection is a major cause of respiratory tract inflammatory lesions. Bacterial examination of sputum and lower respiratory tract specimens is very important significance for diagnosis and treatment of infectious diseases of respiratory system. In order to know the current situation of pathogens in patients with lower respiratory tract infection in Jinhua Central Hospital, In this study we separated593strains of pathogens from sputum from hospitalized patients with lower respiratory tract infections in2013and analyzed drug resistance. To investigate the distribution and drug resistance of pathogens caused lower respiratory tract infections.Methods:A retrospective study in the department of respiratory medicine in our hospital was conducted to analyze the bacterial strains and drug susceptibility for qualified sputum samples from hospitalized patients with lower respiratory tract infections in2013.Results:In total593pathogens were isolated.464strains were gram-negative bacilli (78.2%),49strains were gram-positive bacilli (8.3%), and80strains were fungi (13.5%). Among gram-negative bacilli, the top4common isolates were Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli. The most common gram-positive isolates and fungi were Staphylococcus aureus and Candida albicans, respectively. Regardless of Gram-negative or Gram-positive strain, the isolates display multi-drug resistance.Conclusion:Gram-negative bacilli are the most common pathogens causing lower respiratory tract infections. Multi-drug resistance is very common among the isolates in this study. Clinical physicians should pay more attention to the etiology examination, drug resistance monitoring and rational use of antimicrobial drugs.