The Relationship Between The Different Parts Of Lacunar Infarction Lesion And Cognitive Impairment In Different Fields

Objective To statistic predilection site of lacunar infarction through application of head MRI, and to explore the relevance of cognitive impairment in different areas and lesion site in patients with LI through application of Montreal Cognitive Assessment(MoCA).Methods Select 89 cases of patients with lacunar infarction in different parts and 89 cases with gender, age, education matched normal controls, respectively, using the Montreal cognitive assessment scale to evaluate the cognitive function of these two groups.The demographic data of all cases, the LI lesion site in head MRI and the MoCA score were recorded, the relation between the LI lesion site in head MRI and the sub item and total scores of MoCA were analysed. The results were calculated with SPSS 19.0.Results (1)The head MRI findings showed that the lesion site of patients with LI occurred multiply in basal ganglia, the most common, followed by the centrum semiovale, periventricular white matter, thalamus, then cerebellum, parietal lobe, brain stem, frontal lobe, temporal lobe and occipital lobe are relatively rare.(2) The different intarct lesion sites were related to the different field of cognitive impairment (P<0.05).The damage of temporal lobe lesions were related to the damage of attention and calculation power. The damage of occipital lobe lesions were related to the damage of visuospatial ability, executive function, attention and calculation power. The damage of basal ganglia lesions were related to the damage of visuospatial ability, executive function, attention and calculation power, delayed memory and the decline in total MoCA scores. The damage of thalamus lesions were related to the damage of visuospatial ability, executive function, attention and calculation power, language ability, delayed memory and the decline in total MoCA scores. The damage of periventricular white matter lesions were related to the damage of visuospatial ability, executive function, delayed memory and the decline in total MoCA scores. The damage of cerebellum and brain stem lesions were related to the damage of language ability.Conclusion The most common lacunar infarction lesions in basal ganglia, followed by the centrum semiovale, periventricular white matter, thalamus.The cognitive impairment of patients with Lacunar infarction were various and the cognition of different infarct site were different.