Clinical Safety And Efficacy Of Dapoxetine 30mg Taken As Needed Treatment Of Premature Ejaculation

Objective:To evaluate the demand taking 30mg dapoxetine hydrochloride (trade name:Priligy) treating Chinese patients with premature ejaculation safety and efficacy for 4 weeks.Methods:The study was from April 2014 to March 2015 in our hospital andrology clinic to "find life when rapid ejaculation six weeks to 3 years’ treatment of 114 patients, aged (34.48 ± 7.41) years, the incidence of time (1.6 ± 0.75) years.Study inclusion criteria:(1) the age of 22 years (inclusive) to 64 years (inclusive) of the sexually active heterosexual men. (2) Before entering this study can be understood and patient informed consent form has been signed. (3) the clinical diagnosis of premature ejaculation and you plan to use Dapoxetine hydrochloride tablets in the treatment of patients. (3) The International Index of Erectile Function (IIEF) score≥ 8 (IIEF) patients. (4) physical condition or the patient stable disease state. (5) at least the last six months and during the study stable monogamous sexual relationship with. Exclusion criteria:patients with any of the following one, will not be included in the study patients with contraindications (1) product specifications listed. (2) have been or are currently suffering from mental illness or severe renal impairment. (3) there is a history of alcohol or drug abuse. (4) had other sexual dysfunction (including severe erectile dysfunction:IIEF≤7 points). (5) treatment of premature ejaculation patients are using other methods. (6) Other researchers believe that the case should not be enrolled in the study.Referring to the inclusion criteria and exclusion criteria, the group selected 86 cases. Patients enrolled in sitting blood pressure, heart rate, respiration, height, weight and body temperature had no significant change before and after the study. In this study, non-intrusive, single-arm, open, flexible-dose studies, the drug is dapoxetine hydrochloride tablets 30mg, taken as needed, h before oral sex within (1-3), within 24 hours only doses of 1, treatment for four weeks. If the subject screening qualified, you can enter the day in the screening group, complete the questionnaire schedule a content, a subject in need since the purchase of drugs. After the group of subjects dapoxetine 30mg taken as needed, in the fourth week to complete a visit to the hospital to receive safety and evaluate the effectiveness of the complete contents of Schedule I, if the result is shown to be effective, the treatment end of period, subjects required in the first two weeks after receiving a telephone follow-up, complete Schedule A content to collect after taking safety information.Results:The patient before and after treatment PEP change:72.1% of the patients increased by at least 1 ejaculation control points; 57.6% of the patients sexual satisfaction increased by at least 1; 66.7% of the patients improved at least 1 point of ejaculation distress; 54.5% of patients reported Premature ejaculation impact on the partnership to improve at least 1 minute. Patient vaginal ejaculation latency (IELT) changes inserted into the vagina before treatment 51 cases of patients with ejaculation inside 60s,34 patients within 60-120s ejaculation, more than 1 patient 120s (150s), the mean ejaculatory latency time (74.05 ± 3.83) s, patients after four weeks of treatment in patients with vaginal ejaculation latency time of less than 60s for the 19 cases,60-120s for the 16 cases,120s--300s of 30 cases,21 cases more than 300s, with an average ejaculation latency time (248.54 ± 26.74) s, after treatment intravaginal ejaculatory latency time prolong more than 120s are 51 cases, accounting for 59.30 percent efficiency. Adverse reactions:where the incidence of side effects of dizziness 12 passengers 10.4%, headache 3.4% 3 people, dry mouth occurred two people accounted for 2.3%, fatigue occurred 1 visitors accounted for 1.1%, palpitations,1 person (1.1%), nausea 6 trips occur 6.9%.Conclusion:Dapoxetine can enhance ejaculation control, increase sexual satisfaction, reduce premature ejaculation, distress, and improve partner relationships, after taking a low incidence of adverse reactions,30mg dapoxetine hydrochloride Press need to take to be safe and effective in patients with premature ejaculation.