Qufeng-Zhike Decoction For Treatment Of Post Infectious Cough

Objective:Post infectious cough refers to after acute respiratory symptoms (such as fever, cough, etc.) disappear, the cough persists, usually lasts 3 to 8 weeks. Chest X-ray showed no abnormalities。The cough is self-healing in most cases. It belongs to subacute cough. Clinical infection of subacute cough is the most common type of cough, while cough affect the rest, work and life. Currently recommended treatment the first generation of anti-histamine HI receptor antagonist measures、inhale low-dose hormone or other central antitussives. Montelukast sodium as an oral leukotriene receptor antagonist, can inhibit airway cysteinyl leukotriene (CysLTl) receptor, which can reduce airway inflammation and airway hyperresponsiveness, The traditional Chinese medicine has a long history of treat postinfectious cough, often clinically effective. The experiment by comparing the Qufeng-Zhike-Fang with montelukast, to analyze the efficacy of cough medicine to treat the infection.Methods:Select patients in May 2011 after suffering from infection cough illness in May 2014 admitted to our hospital 84 cases. People randomly divided into control and treatment groups, with an average 42 cases in each group. The control group,25 cases of male patients, female patients 17 cases; patients aged 22-76 years, mean age (46.9 ±1.7) years; duration is 21-56 days, with an average disease duration of 38.64 days; Treatment group,24 cases of male patients, female patients 18 cases; patients aged 21-78 years, mean age (46.7±1.8) years; Upper respiratory tract infection prevalence time 21-56 days, with an average disease duration of 38.98 days. Among these two groups studied natural indicators was no significant difference (P> 0.05), can be compared. And all patients met the inclusion criteria, does not meet the exclusion criteria. Control group:oral montelukast once a day, each time 10mg. Planned to treatment for two weeks. Treatment groups:taking Qufeng-Zhike-Fang,once a day, morning and evening hot drinks.Results:Other symptoms of Airway infection in most cases within three days of the most obvious, one week or so can disappear. However, the presence of persistent cough time longer, in clinical will be called after their infection cough, irritating cough is a characteristic features, Persistence time can reach 1-2 months, or even longer, In the control group, patients with medication (7.12±0.78)d cough symptoms completely disappeared, a total of clinical drug programs implemented (9.89±2.41) d. Between the two groups (P<0.05).Conclusion:According to efficacy, results and statistical analysis shows the clinical efficacy of traditional Chinese medicine and western medicine group, the control group, there were significant differences. Description Qufeng-Zhike-Fang treatment PIC better than montelukast sodium significantly.