Mechanical Simulation Of Neural Electrode-brain Tissue Interface Under Different Micromotion Conditions And Novel Neural Electrodes Design

Micromotion is one of the most important factors that influence the long-term stability of neural electrodes. Firstly, mechanical simulation of NeuroNexus A1x16-3mm-50-177 neural electrode-brain tissue interface under different micromotion conditions were analyzed. The static stress analysis and modal analysis to provide the basic reference for the further optimization design. Then, in order to improve the long-term stability of brain-implanted electrodes, this study designs two novel neural electrodes based on lumped compliance compliant mechanism and small-deflection theory, to control different modes of micromotion in a more effective way. The results revealed that:(1) the novel neural electrode based on lumped compliance compliant mechanism shows excellent micromotion-attenuation capability. The static analysis results showed that the novel design dramatically reduced the maximum displacement of the brain in 43.4% and the maximum stress in 36.6% under longitudinal micromotion environment, and it effectively reduced the maximum stress 11.4% while maintaining the maximum displacement under lateral micromotion environment.(2) the novel neural electrode based on small-deformation theory effects the maximum displacement and the maximum stress of brain tissue. Designing a reasonable size opening area, can effectively improve neural electrode-brain tissue interface under different micromotion conditions, reducing damage to brain tissue, which will extend the electrode life.