The Clinical Value Of PC Cine MRI In Diagnosis And Treatment Of Hydrocephalus

Objective Applied Phase Contrast cine MRI(PC cine MRI) to analyze CSF flow volume, flow velocity, flow curve, absolute stroke volume, the area of the middle section(ampulla) of midbrain aqueduct in cerebral aqueduct plane of normal volunteers, communicating hydrocephalus, obstructive hydrocephalus in different brain parts. Studied the differences of flow characteristics between different groups and discussed the clinical value of using PC cine MRI in diagnosis and treatment evaluation of hydrocephalus.Methords Established normal volunteer group of 5 cases; hydrocephalus group including communicative hydrocephalus of 8 cases, obstructive hydrocephalus of 7 cases(midbrain aqueduct obstruction of 4 cases, the third ventricle of 2 cases and the fourth ventricle of 1 case). Applying philips I n t e r a Achieva 1.5T superconducting MRI and peripheral gating, MRI collected routine brain images and analysis images of CSF flow volume(or flow velocity) respectively. After scanning and inputting, the data was transferred to station MR Extended Workspace R2.6.31. The CSF-QF- Clear software was used to proceed qualitative and quantitative analysis of CSF flow in aqueduct. Compared and analyzes the CSF flow curve, flow volume, flow velocity, absolute stroke volume and the area of the middle section(ampulla) of midbrain aqueduct of different groups.Results 5 cases in normal volunteer group showed sinusoidal waveform in CSF flow curve. 8 cases in communicating hydrocephalus group showed irregular sinusoidal waveform. 4 cases of irregular saw tooth waveform and 3 cases of irregular sinusoidal waveform in obstructive hydrocephalus group(including occupying in the third and fourth ventricle). CSF flow volume(velocity) of normal volunteers group didn’t have statistical significance(P>0.05) with that of hydrocephalus caused by occupying in the third ventricle. CSF flow volume(velocity) of other groups had statistical significances(P<0.05). The areas of midbrain aqueduct of normal volunteer group, communicating hydrocephalus group and obstructive hydrocephalus group caused by midbrain aqueductal stenosis had statistical significance(P<0.05). ASV of communicating hydrocephalus group had statistical significance(P<0.05) with normal volunteer group and obstructive hydrocephalus groups caused by midbrain aqueductal stenosis, occupying in the third and fourth ventricle.Conclusions(1) Normal volunteer group showed sinusoidal waveform in CSF flow curve,communicating hydrocephalus group showed irregular sinusoidal waveform, obstructive hydrocephalus irregular showed saw tooth waveform or irregular sinusoidal waveform.(2) The Region of interest area flow(or velocity) of communicating hydrocephalus is the maximum,the fourth ventricle obstructive hydrocephalus is second, normal volunteers and the third ventricle are third, the cerebral aqueduct stenosis obstructive hydrocephalus is the minimum.(3) The Region of interest area of communicating hydrocephalus is the maximum, the cerebral aqueduct stenosis obstructive hydrocephalus is the minimum.(4) The communicating hydrocephalus’ s absolute stroke volume is the maximum, which ventricular compliance is the worst.