The Meaning Of Procalcitonin When Children With Acute Leukemia Infected During Chemotheropy Mergeing Bone Marrow Suppression

Children acute leukemia is one of the common disease in children tumor diseases.Recently,with the development of chemotherapy as well as the joint bone marrow transplant, the prognosis of leukemia children disease significantly improved. But easy to merge bone marrow suppression during chemotherapy,and extremely easy infection occurs at this time, which is the biggest threat to this kind of children’s long-term survival disadvantage factor. On early diagnosis and treatment of bone marrow suppression after chemotherapy infections become a big challenge, clinically severe infection not only delay time of chemotherapy can be a life-threatening infection is not easy to control at the same time. Procalcitonin as a kind of bacterial infection early sensitive indicators, can be used as children with acute leukemia bone marrow suppression merge infection is one of the early clinical diagnosis method.Objective :To explore the complicated infections in children with acute leukemia bone marrow suppression in different procalcitonin the meaning of the original value.Methods:Use retrospective study method determination of original onset ward a children’s hospital, 102 cases of children with leukemia infection early serum procalcitonin values,according to the types of infection divided into bacterial infection group(50 cases), the bacterial infection group(52 cases), according to the degree of bone marrow inhibitioncaused by infection risk is divided into high-risk risk infection group(75 cases), low latent infection risk group(27 cases), at the same time the clinic of 50 cases of infection and bone marrow suppression for the anti students complete remission of acute leukemia outpatient care patients as controls. To detect the blood routine and procalcitonin value, use the relevant statistical methods such as rank and inspection related comparative analysis.Results:The bacterial infection group of procalcitonin level a median of 0.615 ng/m L, and increases with severe infection, the level of procalcitonin bacterial infection group was obviously lower bacterial infection procalcitonin level, but the level is higher than the control group. Conclusion: the value of the procalcitonin level can be used as children with acute leukemia bone marrow suppression co-infection early diagnosis standard, one of the infection severity can be evaluated as well.Conclusion:The level of the procalcitoninl value can be as bone marrow in children with acute leukemia restrains amalgamative infection early one of the diagnostic criteria, and to evaluate the severity of infection.