Acupuncture Clinical Randomized Controlled Trials For The Treatment Of Tumor Patients With Insomnia

Objective:Evaluate the clinical curative effect of acupuncture and moxibustion treatment of tumor patients with insomnia, status of acupuncture and moxibustion for tumor patients of insomnia and improve sleep quality.Methods:In malignant tumor patients with insomnia as the research object, will be included in the standard according to the time order of the group of patients were randomly divided into acupuncture group and drug control group.In tumor treatment group on the basis of conventional treatment to acupuncture and moxibustion treatment, once per day,30 minutes each time, for seven days to observe the clinical curative effect; The control group in the tumor on the basis of conventional treatment of oral estazolam tablets, take every night before going to bed, for seven days to observe the clinical curative effect; The above two groups of patients in the treatment of follow-up after 7 days. Curative effect evaluation standard, PSQI and MOS-SF36 quality of life table as observation indexes, respectively before and after treatment, follow-up recorded when observation data, and to observe the clinical effect of spssl9.0 statistical software for data statistics.Results:This clinical trials to select 208 cases of tumor patients with insomnia, divided into acupuncture group and drug control group,104 cases in each group, the actual total of 190 patients completed the whole process of clinical trials, including acupuncture and moxibustion treatment group 93 examples, fall off 11 cases; Fall off drug control group 97 cases,7 cases.(1) Two groups of patients before treatment of the baseline situation:gender, age, physical condition (ZPS), Athens insomnia scale (AIS), Pittsburgh sleep quality scale (PSQI) and the quality of life scale (MOS-SF36) is no statistical difference, P> 0.05, comparable. (2) The overall curative effect comparison:after the treatment curative effect more obvious statistical significance between groups, P< 0.05, the control effectiveness is higher than the treatment group; Follow-up curative effect comparison between groups was P< 0.05, there is statistical significance, treatment group effectiveness is higher than the control group; At the time of treatment group after treatment, follow-up curative effect is not significant, P>0.05; Curative effect at the time of the control group after treatment, follow-up comparison (P<0.05, significant statistical significance. (3) Comparison between treatment group: except sleep disorders no statistical significance (P> 0.05 (including PPS nor statistically significant data set daytime dysfunction, P> 0.05), other PSQI scores and all factors have obvious statistical significance. MOS-SF36 life quality comparison, P>0.05, no statistical significance. (4) After treatment group comparison:the treatment group PSQI score and each factor has obvious statistical significance, P< 0.05; MOS-SF36 comparison (P> 0.05, no statistical significance. In addition to wake up is not the control group (P> 0.05), and no statistical significance, other PSQI scores and all factors are obvious statistical significance; MOS-SF36 is no obvious statistical significance, P> 0.05). (5) Followed the group comparison:comparison between follow-up group was waking sleep efficiency, sleep disorder, there were no statistical difference discomfort, P> 0.05, PSQI scores, sleep quality, sleep time, sleep and daytime dysfunction (P< 0.05 significantly statistical difference; MOS-SF36 comparison, no statistical difference, P> 0.05). (6) Follow-up group comparison:After treatment and follow-up group comparison:treatment group total scores of PSQI, each rating factor, MOS-SF36 comparison, there were no obvious statistical significance, P> 0.05; Control group in total scores of PSQI, sleep quality, sleep time, sleep time, sleep efficiency, daytime dysfunction (P< 0.05 has obvious statistical significance, sleep disorder, woke up feeling unwell and MOS-SF36 life quality scale is not significant, P> 0.05). Before treatment and follow-up group comparison:treatment group in addition to the sleep disorder, PSQI scores and other rating factor comparison has the obvious statistical significance (P< 0.05); MOS-SF36 comparison, P> 0.05, no statistical significance. Control group in total scores of PSQI, sleep quality, sleep time, sleep efficiency and daytime dysfunction has obvious statistical significance (P< 0.05), sleep time, sleep disorder and discomfort after waking no obvious statistical significance (P> 0.05); MOS-SF36 comparison, by t test, there was no significant statistical difference (P> 0.05). (7) Comparisons between groups:Safety assessment by the rank and inspection, had no statistical difference (P> 0.05. Two methods of treatment of security.Conclusion:1. Two methods of treatment can obviously improve sleep in tumor patients.2. Recent drug treatment effect is better than that of acupuncture and moxibustion treatment, but the drug group patients prone to wake up feeling unwell; Long-term effect is superior to drug therapy and acupuncture treatment curative effect is stable, no discomfort after waking.3. When the two groups after treatment and follow-up of patients with no obvious improve quality of life condition, it may be related to the patient’s primary disease, emotion, pain degree and so on.4. Safety based on the comparative analysis, two kinds of treatment no serious adverse events occurred, security.