Clinical Efficacy Of Enhanced Recovery After Surgery Combined With Laparoscopy-Assisted Radical Gastrectomy For Gastric Cancer

Objective :To investigate the safety and feasibility of enhanced recovery after surgery combined with laparoscopy-assisted radical gastrectomy for gastric cancer.Method:The clinical data of a total of 98 patients who underwent laparoscopic-assisted radical gastrectomy for gastric cancer were analyzed. Of whom 43 patients accept enhanced recovery after surgery perioperative management(ERAS), while 55 patients accept traditional perioperative management. The following clinical data were recorded:age, sex, tumor size and location, TNM stage, resection extent. The ALB level, white blood cell, CRP level at 1 day before suegery. Intraoperative variables, postoperative recovery and complications rate. The ALB level at 4 day and 7 day after suegery. The pain score at 1day, 2 day and 3 day after suegery, the white blood cell, CRP level at 1 day, 3 day and 5day after suegery. Follw-up was once weekly for 4week.Results:1.There were no significant differences between two groups in sex distribution, age, tumor size and location, TNM stage and resection extent(all P>0.05).2. There were no significant differences between two groups in operation time, blood loss and the number of retrived lymph nodes.3.Compared to LAG group, ERAS+LAG group was associated with quicker recovery of bowel function[(67.75±11.30)h vs.(82.62±14.81)h, t=2.803, P=0.01], shorter postoperative hospital stay[(13.38 ± 4.00)d vs.(17.58±4.08)d, t=2.278, P=0.035], lower hospitalization cost[(5.70±2.01)d vs.(7.58±1.75)d, t=2.209, P=0.040]. However, there were no significant differences in incidence of postoperative complications(11.63% vs.12.73%, χ2=0.027, P=0.869).4. Compared to LAG group, ERAS+LAG group was associated with high ALB level, lower pain score. There were no significant differences in white blood cell count and CRP level(all P>0.05).Conclusion:1.Enhanced recovery after surgery combined with laparoscopy-assisted radical gastrectomy for gastric cancer is safe and feasible.2.Compared to traditional perioperative management, ERAS can decrease postoperative stress response, faster recovery, shorter postoperative hospital stay and lower hospitalization cost.3.ERAS has obvious advantage over traditional perioperative management, and it is worthy to spread.