The Difference Of Risk Factors On Essential Hypertension Patients With Left Ventricular Hypertrophy-ethnic Difference Among Han,uygur And Kazakh Subjects In 3A Grade Hospital Of Xinjiang

Objective: To study the risk factors and the differences in-patients who have essential hypertension with left ventricular hypertrophy from Han, Uygur and Kaza kh ethnic groups in Xinjiang province. Methods: Patients from the First Hospital of Xinjiang Medical University with essential hypertension during January 2013 to January 2015 were randomized into three groups according to ethnic differences, a nd then every group was divided into two subgroups. Compared the difference of blood parameters and ambulatory blood pressure parameters in different groups. R esults: In Han left ventricular hypertrophy group, serum cystatin C and homocyste ine were higer than non-left ventricular hypertrophy group, while folic acid was lo wer than non-left ventricular hypertrophy group(P<0.05). In Uygur left ventricular hypertrophy group,serum cystatin C、fibrinogen and homocysteine were higher tha nnon-left ventricular hypertrophy group(P<0.05). In Kazakh left ventricular hypertr ophy group, serum cystatin C、fibrinogen and homocysteine were higher than nonleft ventricular hypertrophy group(P<0.05). Comparaed with Han left ventricular h ypertrophy group, Uygur had a lower level of folic acid and Vitamin D(P<0.05),Kazakh had a lower level of folic acid(P<0.05). In Han left ventricular hypertr ophy group, 24 hours systolic blood pressure(24hSBP)、24 hours diastolic blood pr essure(24hDBP)、24 hours pulse Pressure(24hPP)、day mean systolic blood pressur e(dSBP)、day mean diastolic blood pressure(dDBP)、day mean pulse Pressure(dPP)、night mean systolic blood pressure(nSBP)、night mean diastolic blood pressure(dDBP)、night mean pulse Pressure(nPP)were higher than non-left ventricular hypertroph y group(P<0.05). In Uygur left ventricular hypertrophy group, 24hSBP、24hPP、d SBP、dPP、nSBP、nDBP、nPP were higher than non-left ventricular hypertrophy group(P<0.05). In Kazakh left ventricular hypertrophy group, 24hSBP、24hPP、dP P、nSBP、nDBP、nPP were higher than non-left ventricular hypertrophy group(P<0.05). Comparaed with Han left ventricular hypertrophy group, Uygur had a lower24hDBP、dDBP、nDBP level. Logistic regression showed that Uygur and Kazakh,24-hour systolic blood pressure, 24-hours pulse pressure,serum cystatin C and fibri nogen of Uygur and Kazakh were the significantly independent determinants for le ft ventricular hypertrophy. While the females seemed a protective factor. Conclusio n: The prevalence of left ventricular hypertrophy is different among ethnics and d ifferent between males and females. These results implied that a comprehensive int ervention should be taken in the prevention of left ventricular hypertrophy.