Research On The Relationship Between Obstruction Sleep Apnea Hyponea Syndrome And Nasal Resistance

Objective The purpose of this study to investigate the relationship between obstruction sleep apnea hyponea syndrome(OSAHS) and anterior rhinomanometry induced nasal resistance.Methods Between May 2014 and December 2015, sixty patients (males) who were admitted with complaints of snore, breathing pauses told by their partners, oversleep mood in a daytime and fatigue and diagnosed with OSAHS by polysomnography were prospectively enrolled. Patiens were divided into nasal obstruction group(n=30) and without nasal obstruction group(n=30). Anterior rhinomanometry was applied for all patients and nasal resistance was estimated.Results OSAHS with nasal obstruction and without nasal obstruction group show no significant deference with apnea hyponea index(AHI), lowest oxygen saturation (LSaO2) and average oxygen saturation (ASaO2). However, the sleep arousal and structure was significantly disturbed. A significant relationship between expiratory total resistance(Exp total) and total sleep arousal (P=0.037), arousal index(AI) (P =0.032), percentages of stage 3-4 non-REM sleep (N3+N4,%) (P=0.044) was observed in OSAHS patients with chronic nasal obstruction. The values of Exp total increased, the total sleep arousal and AI increased, while N3+N4(%) decreased significantly. whereas inspiratory total resistance (Insp total) was not associated with any sleep parameters of PSG.Conclusion OSAHS with chronic nasal obstruction compared with without chronic nasal obstruction, the sleep arousal and structure was significantly disturbed but the severity of OSAHS have no significant difference. Nasal obstruction may have effect on sleep disruption in OSAHS. Nasal expiratory resistance increased may be an important risk factor for arousal from sleep and disturbance of sleep architecture in OSAHS patients.