The Features Of Clinical, Pathology And The Evaluation Of Endoscopic Therapy On Gastrointestinal Mesenchymal Tumors

Objective: To investigate the clinical, pathologic and endoscopic features of gastrointestinal mesenchymal tumors,and to further evaluate the safety and efficacy of different methods in treating gastrointestinal mesenchymal tumors(GIMTs) with endoscope.Methods: The clinical data of 46 GIMTs patients treated in October 2014 to March2015 in our hospital were retrospectively analysis, in detail, analyze their clinical,pathologic features and outcomes.Results: Lesions mainly located in the middle and lower segment of esophagus, which mainly derived from mucous layers and performed for leiomyomas. GIMTs mainly performed for swallowing obstruction and behind the sternum discomfort in clinical.Thirty-six of 46 cases conducted EMBM treatment, whose tumors derived from mucous layers and the diameter of tumors were less than 2.0 cm. All of the tumors were one-time removed completely and only one case undergone a small amount of bleeding. Three cases conducted ESD treatment whose tumors derived from mucous layers and the diameter of tumors were more than 3.0 cm. All of the three tumors were one-time removed and no bleeding and perforation complications. Three cases conducted ESE treatment whose tumors derived from lamina proprias. All of the tumors were one-time removed, with one case perforation(0.2 cm) but no bleedingcomplication. Four cases conducted STER treatment whose tumors derived from lamina proprias. All of the tumors were one-time removed with no complications occurred. All of the 46 patients were cured through review after 1 to 3 months of operations. No residual tumor, recurrence and narrow.Conclusion: Endoscopic treatment is safety and effective for patients with GIMTs.Patients with smaller tumor(the diameter is less than 2.0 cm) conduct EMBM could achieve the same effect of ESD. Patients with lager tumor(the diameter is more than2.0 cm) could adopt ESD treatment. GIMTs derived from lamina propria could be one-time removed and the risk of perforation is increased accordingly, but the perforation is commonly small and could be prevented by hemostatic clip.