Analysis Of Clinical Features Of Granulomatous Lobular Mastitis With Ductal Dilatation

ObjectiveThis research through the analysis of ductal dilatation of granulomatous lobular mastitis (ductal dilatation of the GLM) in patients with the clinical features, and the exploration of the difference among ductal dilatation of the GLM、 simple granulomatous lobular mastitis (simple GLM), plasma cell mastitis (PCM), to sum up the clinical manifestations of the three specific, to provide clinical diagnosis and differential diagnosis of provide reference for further follow-up studies.methodWe conduct the retrospective analysis of the inpatients with granulomatous mastitis GLM with ductal dilatation who received treatment from Guangdong Provincial Hospital of Chinese Medicine from 2009 to 2015.We discusse the clinical manifestations of GLM with catheter dilation, through the study of GLM with catheter dilation, simple GLM and PCM. We collect the the age, fertility, lactation and anamnesis, lesion location, the development of nipple, the deformity of nipple, local inflammation of the breast, constitutional symptom, stage of Chinese Medicine, Traditional Chinese Medicine syndrome differentiation and typing, the data we record in SPSS 17.0 and analyzed by SPSS 17.0. result1.It is closely related to reproductive history for ductal dilatation of the GLM, compared with the general GLM, the difference was not significant. Compared with the PCM, the difference is statistically significant (P= 0.011). It is closely related to lactation history for ductal dilatation of the GLM, and there is no significant difference with simple GLM or PCM.2. Compared with general GLM, the GLM with ductal dilatation have longer lactation time, it’s lactation time is 9.35±9.55 months, the simple GLM is 6.93±4.14) and PCM is 11.00±8.19, the difference is not obvious; simple GLM lactation time concentrated within 1 year.3. The GLM with ductal dilatation have longer duration, the course number is 5.92±10.22 months.compared with general GLM(2.57±0.18), the difference is statistically significant (P= 0.001), compared with the PCM (7.87±14.14), the difference is not obvious.4. The GLM with ductal dilatation often occur in the end of the incidence of catheter expansion/lactation time more concentrated in the 0-5 years, especially in 0-3years, compared with the general GLM and PCM, the difference is not obvious.5. The GLM with ductal dilatation often occur in the peripheral quadrant of the breast, it is similar with general GLM, but the difference was statistically significant compared with PCM (p=0.009) PCM was mainly occur around the nipple.6. Some of the GLM with ductal dilatation come on with nipple abnormalities, it is similar to simple GLM, compare with PCM, the difference was statistically significant (p=0.009 )and most of the patients with nipple abnormalities.7. Erythema of the extremities can occur in the GLM with ductal dilatation, it is similar to the simple GLM, while PCM no one have this feature.8.Toxic heat flourishing is the main type of traditional Chinese medical syndrome, syndrome of yang deficiency and coagulated phlegm ranked the second.it is similar to simple GLM, compare with PCM, the difference was statistically significant(P= 0.014).ConclusionIn clinical manifestations, the GLM with catheter dilation is close to the simple GLM, compared to the simple GLM, the GLM with catheter dilation have long duration and feeding time is long.GLM with catheter dilation often occurs in young women, it has a closely related to the recent history of reproduction and lactation, its feeding time is long,it has a long duration,it often occurs in the peripheral quadrant of the breast, it also occurs occur around the nipple, Some of the GLM with ductal dilatation come on with nipple abnormalities, nipple secretion, pain, the mass is the local expression of the initial incidence of GLM, systemic symptoms may be associated with fever, erythema of the extremities, toxic heat flourishing is the main type of traditional Chinese medical syndrome.The GLM with catheter dilation may have a connect with a long feeding time and the progression of disease. The specific pathologic findings of PCM are not considered in the consideration of ductal expansion.