Clinical Efficacy Of Eliminating Phlegm By Cooling Of TCM To Perioperative Period Of Non-small Cell Lung Cancer

ObjectiveThe purpose of this study is to find if Eliminating Phlegm by Cooling of TCM can improve the immunologic function, inflammation, postoperative rehabilitation in perioperative period of Non-small cell lung cancer, Through retrospective analysis of clinical efficacy. To explore further about the value of Eliminating Phlegm by Cooling of TCM in perioperative period, and to provide scientific and objective clinical studies about the clinical application.MethodsThe clinical data of 55 patients with Non-small cell lung cancer at The First Affiliated Hospital of Guangzhou University of TCM between January 2012 and February 2016 were retrospectively analysed. Patients were dicided into two groups:the Eliminating Phlegm by Cooling of TCM group and the routine medication group. The 30 patients in Eliminating Phlegm by Cooling of TCM group were giving conventional treatment(anti-infection, Nutritional Support) and traditional Chinese decoction(over 1 week);The 25 patients in routine medication group were giving conventional treatment only.We observed the variation tendency of hemanalysis in perioperative period(the day before treatment, lth day、2th day、3th day postoperative), postoperative complications between two groups; the first time of defecation postoperative between two groups and so on. All the date were using SPSS22.0 statistics analysis.ResuItsBy comparison, There were significant differences about the cross effect of use of Eliminating Phlegm by Cooling of TCM and time between the two groups in lymphocytes counting^ NLR and PLR. Also there were significant differences about the cross effect of treatment measures and time within-group comparison in lymphocytes countings NLR and PLR.However, in the comparison of every point of time, there were significance difference between the the two groups in lymphocytes counting of the 2th day postoperative (P=0.04)、the 3th day postoperative (P=0.04). There were no significant differences between the two groups in lymphocytes counting of the day before treatment, lth day postoperative. There were no significant differences between the two groups in NLR and PLR of the day before treatment, lth day postoperative;however, there were significant difference between the the two groups in NLR (P=0.04) of the 2th day postoperative^ the 3th day postoperative (P=0.01). There were significant difference between the the two groups in PLR (P=0.02) of the 2th day postoperative^ the 3th day postoperative (P=0.01). There were significance difference between the the two groups about the first time of defecation postoperative (P=0.01); There were no significant differences between the two groups in Postoperative rehabilitation score in Peroperative Period (P=0.65).NLR and PLR comparisons of intra-group both showed the downtrend along with the time postoperative.ConclusionThe result shows that the using of Eliminating Phlegm by Cooling of TCM can improve the immunologic function, inflammation, postoperative rehabilitation in perioperative period of Non-small cell lung cancer. However it need more further randomized clinical research to confirm the result.