Acupuncture And Cerebral Ultrasound Therapy On Infants With Brain Damage Syndrome:A Clinical Research

BackgroundBrain damage syndrome (BDS) is a set of neurological syndrome that caused by perinatal non-progressive brain damage, which is a transitional diagnosis for high-risk children with neurological symptoms. This concept is proposed to apply early intervention on high-risk children who are temporarily not diagnosed as cerebral palsy, and to avoid excessive diagnosis and treatment. Because infants within lyo are in a stage of rapid development of the brains and their brains’plasticity and reparability is incomparable to those who are older than lyo, it will reduces the incidence of neurological disorder by apply early intervention within this timing. Therapies of early intervention are various and vary from effectiveness. Chinese medicine has its huge potential in this field, so it’s well worth to discuss which combined therapy of Chinese and modern medicine is more effective.ObjectiveTo observe whether combination of acupuncture and cerebrovascular ultrasound therapy has synergistic effect, comparing to single acupuncture or single cerebrovascular ultrasound therapy. To evaluate the application of combination of acupuncture and cerebrovascular ultrasound therapy on BDS, assessed by mental development level, motor development level and changes in cerebral hemodynamics.MethodsA total of 90 cases of infants with BDS were involved in this study, selected from GZUCM Nanhai Maternity Children’s Hospital, from Jan 2015 to Oct 2015. All cases were randomly divided into 3 groups (30 each). All 3 groups received basic rehabilitation (PT, Tuina, Chinese herb spa, somatosensory music, visual and acoustic stimulation and early teaching), and group A received acupuncture and cerebrovascular ultrasound therapy, and group B received acupuncture, and group C received cerebrovascular ultrasound therapy. Each course continued by 20 days, and there were totally 3 courses, and an interval of 10～15 days. Before and after the treatment, all cases were assessed by TCD, Gesell and GMFM. Eventually 83 cases were included in the statistical analysis, including 28 cases in group A,28 cases in group B and 27 cases in group C. All results were analyzed by SPSS 22.0.Results1). TCD results shows that Vs and Vm of 3 groups significantly increase while PI and, RI significantly reduce. Degree of improvement in group A is significantly better than that of group B and C (p>0.05).2). Social adaption DQ and personal adaption DQ of all 3 groups significantly increase. And Degree of improvement in group A is significantly better than that of group B and C (p>0.05).3). Social gross motor DQ, fine motor DQ and total scores of GMFM of all 3 groups significantly increase. And Degree of improvement of gross motor DQ and total scores of GMFM in group A is significantly better than that of group B and C (p>0.05). Improvement of fine motor DQ has no significantly difference among 3 groups.4). Speech/language DQ of all 3 groups significantly increase. But improvement of 3 groups has no significantly difference.5). Short-term follow-up shows that incidence of neurological sequela in group A is significantly lower than in group B and C (p<0.05).ConclusionCombination of acupuncture and cerebrovascular ultrasound therapy with routine rehabilitation is effective in treating BD. Acupuncture and cerebrovascular ultrasound therapy has a synergistic effect, which is better than single therapy. The set of therapies facilitates outcome in many domains, such as mental development, motor development, and blood supply of brain, and it plays an active role in the prevention of neurological sequela. Thus, Combination of acupuncture and cerebrovascular ultrasound therapy with routine rehabilitation is clinically effective, safe and practical.