Differentiating Breast Lesions With ADC Value Of Fluid Area

Objectives:To investigate the value of fluid areas apparent diffusion coefficient ADC) in differential diagnose of breast lesions.Process:Breast lesions were pathologically confirmed 54 cases (28 cases of malignant tumors,13 cases of benign tumors,13 cases of inflammatory lesions), preoperative magnetic resonance diffusion weighted imaging (DWI) scan. Measurements in different regions fluid lesion ADC value and using single factor analysis of variance (one-way ANOVA) method to compare the mean ADC value difference in the three groups of breast lesions. Using receiver operating characteristic curve (ROC), analysis of fluid areas ADC value diagnostic accuracy of breast cancer, benign tumors and inflammatory lesions.Results:The mean ADC values of fluid areas in malignant tumors, benign tumors and inflammatory lesions were (2.03±0.52), (1.99 ± 0.56) and (1.17 ± 0.66) × 10-3mm2/s respectively (F= 11.242, P<0.01). An fluid area ADC value≥ 1.61 × 10-3mm2/s was used as the threshold for malignant tumors, with a sensitivity of 89% and specificity of 77%. An fluid area ADC value≥ 1.32 X 10-3mm2/s was used as the threshold for benign tumors, with a sensitivity of 85% and specificity of 69%. An fluid area ADC value≥1.61 X 10-3mm2/s was used as the threshold for tumors (both benign tumors and malignant tumors), with a sensitivity of 83% and specificity of 77%.Conclusion:Analysis of breast lesions fluid areas ADC value, can help to improve the differential diagnostic value of benign and malignant tumors and inflammatory lesions.