The Research Of Flash Visual Evoked Potentials Noninvasive Measurement Of Intracranial Pressure Applied To Treat Severe Craniocerebral Injury

Objective: To research the effect of the application of Flash Visual Evoked Potentials noninvasive measurement of intracranial pressure in treating severe craniocerebral injury and its influence in the prognosis of the injury. Methods: Firstly, in the department of neurosurgery of the affiliated hospital of Guilin Medical University, we chose randomly 40 patients appropriated to be carried out lumbar puncture from October 2013 to February 2014, with FVEP( Flash Visual Evoked Potentials) noninvasive intracranial pressure monitoring, and then performing the lumbar puncture measure immediately. We obtained the corresponding data, respectively, to compare the differences between the groups. Secondly, in the same hospital, we collected 120 patients with the GCS score range from 3 to 8, this data came from March 2014 to May 2015, which divided into experimental(60 patients) and control(60 patients) groups. Collecting the data of non-invasive intracranial pressure monitoring, clinical outcomes and imaging files for the experimental group, and the control group is free of noninvasive intracranial pressure monitoring. We had completed 3-month-followup after they left hospital, with the GOS score to compare the difference intergroup. Results: In the former experiment the ruslut of the noninvasive measurement of intracranial pressure was 185.75±11.31(mmH2O),the ruslut of measurement of the lumbar puncture was 182.25±10.56(mmH2O),rusluts of the two groups were compared by T-test,T=-0.272,p>0.05,There was no statistical difference(p >0.05)between the noninvasive intracranial pressure monitoring and the lumbar puncture measure, but they have correlation, r=0.951,p < 0.01, for the followed experiment, There was no statistical difference(P>0.05) in age、weight、sex ratios between experimental and control groups before the treatment, The prognosis and the factors were anlysed by logistic regression, the factor of the appliment of the noninvasive intracranial pressure monitoring had the most distinct effect on the prognosis,OR=0.43,the confidence interval of 95%was(0.13,0.86),it indicated that : the appliment of the noninvasive intracranial pressure monitoring could make the distinct function of protction in the prognosis,the other factors have no distinct influence in the prognosis.By eliminating other factors,the prognostic score of GOS of experimental and control groups were compared by chi-square test,χ2=15.740,P<0.01, there was a statistical difference(P <0.05) in the prognostic score of GOS, demonstrating that the experimental obvious priority to the control. Conclusion: The noninvasive intracranial pressure monitoring can reflect correctly the intracranial pressure, when applied to treat severe craniocerebral injury, there will be a dictinct promotion of the prognosis of patients.And it can monitor for the typical and crtical craniocererbral injury accurately and succefully, its prospct of application is spacious.