| Objective:To understand the infection of Toxoplasma gondii among women of childbearing age in Ningbo, and analyze the antibody positive patients’epidemiology and the clinical manifestations, and explore the prognosis after the drug intervention, in order to provide scientific evidence for drawing up control strategics.Methods:680 case of fertile women are used to measure of Toxoplasma gondii antibody by the methods of ELISA and IHA, analyze the antibody positive patients’ epidemiology and diagnosis and treatment.Results:The positive rate of Toxoplasma antibody is 6.18%(42/680) among 680 cases of fertile women in Ningbo. There Is no statistical significance between age, occupation, culture and residence (P>0.05). Positive infection were susceptible factors. The antibody positive proportion are respectively,57.14%,26.19%,16.67% among keeping pets, eating raw food, engaged in breeding and supply of meat. Acetylspiramycin in the treatment of Toxoplasma gondii improved the liver function and no serious adverse reaction, the antibody titer of 1:64 positive patients was not elevated, and the antibody titer of 1:256 and 1:1024 positive patients decreased to 1:64.Conclusion:There is certain positive rate of Toxoplasma gondii antibody among the fertile women in Ningbo. It is very important for fertile women to accept health education and serological detection of toxoplasmosis and treatment of positive patients in time. |