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Efficacy Of Indirect Revascularization Procedures For Treatment Of Hemorrhagic Moyamoya Disease

Posted on:2017-04-02Degree:MasterType:Thesis
Country:ChinaCandidate:B ZhengFull Text:PDF
GTID:2284330488996899Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objectives:In this study, the evaluating of the mRS (Modified Rankin Scale) to the hemorrhagic moyamoya patients treated by indirect revascularization before and after operation and analysis of postoperative patients with DSA results. statistical methods were used to evaluate the effective of the encephalo-duro-arterio-synangiosis (EDAs) treatment of hemorrhagic moyamoya disease.Methods:I have collected the clinical and imaging data of the patients in 15 cases from January 2014 to June 2015 October, who had been hospitalized in Department 1 of Neurosurgery,The first hospital affiliated of Kunming medical University with hemorrhagic moyamoya disease treating by the encephalo-duro-arterio-synangiosis (EDAs). All patients were examinating by DSA before ope ration, and the effectiveness of postoperative vascular reconstruction was evalua ted according to DSA after the operation. mRs score were used to evaluate the Clinical function, the mRS which before 1 day and after 6 months operatio n were compared. All patients were followed up for perioperative and postoper ative complications.Results:the mRS which before 1 day and after 6 months operation tested by Wilcoxon Signed Ranks test, Z=-3.391 and there was significant difference between them (P<0.05,CI 95%).which suggests that the situation is improved sigllificantly 6 months after surgery, and The effective rate of postoperative vascular reconstruction was 53.33%.Conclusions:1.Indirect Revascularization Procedures could revascularize and improve the symptoms and of hemorrhagic moyamoya disease patients, by the remodeling of intracranial and extra cranial vascular.2. The main reason that the moyamoya vessel, the small artery aneurysm and the AChA-PComA expansion may be the main reason of hemorrhagic moyamoya disease patient to bleed again, successful blood flow reconstruction can reduce the rate of rebleeding by eliminating the risk factors.
Keywords/Search Tags:Moyamoya disease, Hemorrhagic, Clinical manifestation, Digital subtraction angiography, vascular reconstruction, Prognosis
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