The Study On The Risk Factors Of Diabetic Patients Causing Lower Extremity Arteriosclerotic Occlusive Disease

Objective The pathogenesis of diabetic patients causing lower extremity Arteriosclerotic occlusive disease is complex, and progression of that is rapid, treatment is not satisfactory.The majority of patients is developing diabetic foot, gangrene, and ultimately facing amputation or cut toe.Studying the effect of diabetic patients correlated with lower extremity arteriosclerosis occlusive disease risk factor analysis. In order to better guide clinical early intervention, slow disease progression and improve the quality of life of patients.Methods In our hospital, November 2012 to November 2014, 55 cases of diabetic patients correlated with lower extremity arteriosclerosis occlusive disease were analyzed retrospectively, these patients as experimental group, another selection of 55 cases of diabetic patients with lower limb arteriosclerosis occlusion disease as control group, the two groups of patients with risk factors of diabetic lower limb arteriosclerosis occlusion relationship.Results The results in single factor analysis showed that age, smoking history, course of the disease, high blood pressure(HBP), fasting plasma glucose(FPG), glycosylated hemoglobin(HbA1c), three acyl glycerin(TG), total cholesterol(TC), high-density lipoprotein(HDL-C), low-density lipoprotein(LDL-c), lipoprotein alpha(Lp alpha), apolipoprotein A1(ApoA1), apolipoprotein B(ApoB), blood uric acid(BUA), with coronary heart disease(CHD), diabetic peripheral neuropathy(DPN) with the onset of diabetic patients correlated with lower extremity arteriosclerosis occlusive disease had varying degrees of positive correlation(P< 0.05). Multiplefactor analysis, smoking history, HBP, FPG, HbA1 c, TG, TC, LDL- C, ApoA1, ApoB, CHD, DPN were the main risk factors, with statistical significance(P < 0.05).Conclusions The patient’s smoking history, HBP, FPG, HbA1 c, TG, TC, LDL- C, ApoA1, ApoB, CHD, DPN is diabetic lower limb arteriosclerosis occlusion disease risk factors, and ApoB, LDL- C is the most significant.