Long-term Follow-up Study Of Anticoagulant Therapy In Patients With Pulmonary Thromboembolism

Objective:To investigate the long-term prognosis of anticoagulant therapy in patients with follow-up situation and related risk factors affecting the prognosis,and To help clinicians improve the level of understanding of PTE standardized treatment.Methods:For January 2012 to December 2014 in Shanxi Medical University Hospital Respiratory hospital diagnosed 254 cases of pulmonary thromboembolism(PTE) in patients with follow-up studies, The patients were followed up for 12 months after discharge. patient follow-up analysis PTE situation, and complete follow-up 106 cases according to the clinical outcome differences divided into two groups: good prognosis group and poor prognosis group to explore the long-term anticoagulant therapy in patients with PTE prognosis and risk factors affect prognosis.Results:Follow up: Complete follow-up of the number of cases 106 cases(41.7%), the number of cases lost 148 cases(58.3%). During follow-up, 47 cases(44.3%) were followed up, and 59 patients(55.7%) were followed up. Female patients were followed up the success rate is higher than that of male patients(P < 0.05), urban residents follow-up success rate is higher than that of rural residents(P < 0.005) tall and high-risk groups of patients were followed up for success rate(62.5%) was significantly higher than that in, low-risk groups(47.7% and 33.6%, respectively, P < 0.05).Long term prognosis: 106 cases completed follow-up cases, good prognosis group of 84 cases(79.2%), mean age(50.5 + 12.1) years old, poor prognosis group of 22 cases(20.8%), mean age(56.3 + 10.3) years old. The age difference between the two groups was statistically significant(P=0.047). There was significant difference between the two groups in patients with underlying diseases, such as deep vein thrombosis(DVT), tumor, ovarian excessive stimulation syndrome(P < 0.05). There were significant differences between the two groups in the right ventricular dysfunction(P=0.000), clinical classification(P=0.002) and CTPA perfusion defects() in the number of lung segments(P=0.025). There were significant differences between the two groups in the hospital education(P=0.008) and medication compliance(P=0.000).Multivariate Logistic regression analysis, combined with tumor, DVT and right ventricular dysfunction may be the risk factors for long-term prognosis of patients with PTE.Conclusions:1. The overall follow-up of PTE was poor, and the factors influencing the follow-up were gender, residence and newly diagnosed. The follow-up rate was high in female, urban residents and high risk groups.2.Combined tumor, DVT and the presence of right ventricular dysfunction may be the risk factors for long-term prognosis of patients with PTE.3.During the period of hospitalization of specialist patients and their families to cope with strengthening PTE on the relevant knowledge, improve the treatment compliance of patients, improve the prognosis of patients with PTE.